Many different approaches are utilized in the study of programmed cell death or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach to assessment of apoptosis. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery.

Our range of apoptosis assays for flow cytometry offer you: 

  • Superior performance—highly sensitive assays to detect early to late events
  • Diverse selection—large number of assays to detect different parameters
  • Convenient—ready to use assays with validated flow cytometry protocols
  • Compatible—many fluorescent options for multiple laser excitation sources

Apoptosis assays selection guide

Plasma membrane assays

Plasma Membrane Assays   Annexin V conjugates, new ratiometric assays, monomeric cyanine dyes.

Caspase assays

Cytoplasm Assays   Caspase assays, PARP assays, antibodies for caspases.

Mitochondrial assays

Mitochondrial Assays   JC-1 assays, membrane potential assays, transition pore assays.

Nuclear apoptosis assays

Nuclear Apoptosis Assays   DNA fragmentation, DNA condensation, TUNEL assay.

Multiparametric apoptosis assays for flow cytometry

Our multiparametric apoptosis assay kits are designed to selectively differentiate apoptotic cells from living and necrotic cells in a single cell population.

Apoptosis and viability scientific posters