Single-step purification of many antibody formats

CaptureSelect™ Antibody Toolbox® products are designed to enhance the success of your antibody purification processes. The products offer specific advantages over purification using Proteins A, G, and L, including unique target specificity and simplified elution protocols. Each product has defined target specificity for distinct antibody types and regions, minimizing the need for you to test multiple media products to determine the optimal choice. Learn more about these products or view our latest publication Pure Potential on IPT.


CaptureSelect™ Antibody Toolbox® resins for biomolecule purification

IgG, all subclasses Characteristics
CaptureSelect™ IgG-CH1 (resin) Suitable for purification of human IgG and all Fab fragments
CaptureSelect™ IgG-CH1 (pre-packed column) Suitable for purification of human IgG and all Fab fragments
CaptureSelect™ FcXL Specific for human IgG, recognizing all four subclasses, offering mild elution conditions
CaptureSelect™ IgG-Fc (Hu) Specific for human IgG, recognizing all four subclasses
CaptureSelect™ IgG-Fc (ms) Designed to purify IgG from multiple species by high-affinity binding to the Fc region of IgGs
Light chains Characteristics
CaptureSelect™ KappaXL To purify all human kappa Ig light chain–containing products, offering mild elution conditions
CaptureSelect™ LC-kappa (Hu) To purify all human kappa Ig light chain–containing products
CaptureSelect™ LC-kappa (mur) Murine Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments, and poly Ig from mouse, rat, and guinea pig
CaptureSelect™ LC-lambda (Hu) To purify all human lambda Ig light chain–containing products
CaptureSelect™ LC-lambda (ung) Suitable for Ig, Fab fragments and free light chains from ungulates (bovine, horse, donkey, sheep, goat, pig)
CaptureSelect™ LC-lambda (mouse) Mouse Ig binder recognizing IgG, IgM, IgA, IgD, IgE, and Fab fragments containing a lambda light chain from mouse
CaptureSelect™ LC-lambda (rat) Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments containing a lambda light chain from rat or guinea pig
Isotype-specific Characteristics
CaptureSelect™ IgM IgM resin suitable for human, mouse, and rat IgMs
CaptureSelect™ IgA For purification of human IgA, IgA dimers, and secretory IgA (sIgA)
CaptureSelect™ IgA-CH1 (Hu) For purification of human IgA, IgA dimers, and secretory IgA (sIgA) and Fab fragments thereof
IgG subclass–specific Characteristics
CaptureSelect™ IgG4 (Hu) Specific for human IgG4 without any cross-binding to other subclasses or species
CaptureSelect™ IgG1 (Hu) Specific for human IgG1 without any cross-binding to other subclasses or species
CaptureSelect™ IgG3 (Hu) Specific for human IgG3 without any cross-binding to other subclasses or species
IgG, all subclasses Characteristics
CaptureSelect™ IgG-CH1 (resin) Suitable for purification of human IgG and all Fab fragments
CaptureSelect™ IgG-CH1 (pre-packed column) Suitable for purification of human IgG and all Fab fragments
CaptureSelect™ FcXL Specific for human IgG, recognizing all four subclasses, offering mild elution conditions
CaptureSelect™ IgG-Fc (Hu) Specific for human IgG, recognizing all four subclasses
CaptureSelect™ IgG-Fc (ms) Designed to purify IgG from multiple species by high-affinity binding to the Fc region of IgGs
Light chains Characteristics
CaptureSelect™ KappaXL To purify all human kappa Ig light chain–containing products, offering mild elution conditions
CaptureSelect™ LC-kappa (Hu) To purify all human kappa Ig light chain–containing products
CaptureSelect™ LC-kappa (mur) Murine Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments, and poly Ig from mouse, rat, and guinea pig
CaptureSelect™ LC-lambda (Hu) To purify all human lambda Ig light chain–containing products
CaptureSelect™ LC-lambda (ung) Suitable for Ig, Fab fragments and free light chains from ungulates (bovine, horse, donkey, sheep, goat, pig)
CaptureSelect™ LC-lambda (mouse) Mouse Ig binder recognizing IgG, IgM, IgA, IgD, IgE, and Fab fragments containing a lambda light chain from mouse
CaptureSelect™ LC-lambda (rat) Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments containing a lambda light chain from rat or guinea pig
Isotype-specific Characteristics
CaptureSelect™ IgM IgM resin suitable for human, mouse, and rat IgMs
CaptureSelect™ IgA For purification of human IgA, IgA dimers, and secretory IgA (sIgA)
CaptureSelect™ IgA-CH1 (Hu) For purification of human IgA, IgA dimers, and secretory IgA (sIgA) and Fab fragments thereof
IgG subclass–specific Characteristics
CaptureSelect™ IgG4 (Hu) Specific for human IgG4 without any cross-binding to other subclasses or species
CaptureSelect™ IgG1 (Hu) Specific for human IgG1 without any cross-binding to other subclasses or species
CaptureSelect™ IgG3 (Hu) Specific for human IgG3 without any cross-binding to other subclasses or species

Learn more about CaptureSelect(tm) affinity products and services