Analyze CYP2D6 copy number variants with the QuantStudio™ 12K Flex Real-Time PCR System. TaqMan® Copy Number Assays use TaqMan® MGB probe chemistry to obtain specific, reproducible, and easy-to-interpret copy number results for important pharmacogenomic genes such as CYP2D6.

Life Technologies provides a broad product family to extend your research to other important pharmacogenomic variants:

  • Predesigned TaqMan® Copy Number Assays
    • Human: over 1.6 million predesigned assays available for genome-wide coverage
    • Mouse: over 180,000 predesigned assays available for gene exons
  • Custom Plus TaqMan® Copy Number Assays
    • Submit user-defined human or mouse genomic targets for custom assay design, including upfront bioinformatic sequence analysis and in silico QC
  • Custom TaqMan® Copy Number Assays for other targets of interest
    • Submit any masked target sequences for assay design
    • Submit primer/probe pair sequences for assay synthesis

Experimental Workflow: Find the Products You Need for Every Step

Purify the DNA using MagMAX™ technology

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  • MagMAX™ DNA Multi-Sample Kit
    MagMAX™ DNA Multi-Sample Kits are designed for rapid purification of high-quality genomic DNA from a variety of sample types including blood, blood cards, and buccal swabs. These purification kits use MagMAX™ magnetic bead–based nucleic acid isolation technology to produce high yields of purified DNA, free from inhibitors that may affect downstream reactions such as genotyping assays.
  • MagMAX™ Express Magnetic Particle Processors
  • MagMAX™ accessories

Select your TaqMan® Copy Number Assays using our assay search tool.

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Perform real-time plate amplification and read using the QuantStudio™ 12K Flex system with the 384-well, Fast 96-well, or 96-well block.

Whether you need installation qualification and operation qualification (IQ/OQ) or instrument performance verification (IPV), our qualification services help you verify that your instrument is working according to manufacturer’s specifications, thereby allowing you to produce audit-quality data to share with regulatory agencies.

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CopyCaller® Software analyzes data generated on the QuantStudio™ 12K Flex platform to determine the number of copy variants for each target analyzed. AlleleTyper™ Software converts copy number results into star-allele results.

CopyCaller® Software can:

  • Open copy number experiment absolute quantitation data collected by most real-time instruments from Life Technologies
  • Perform copy number analyses with or without a known calibrator sample
  • Report confidence in individual or grouped copy number calls
  • Display the calculated sample copy number data in both table and graphic formats
  • View detailed data analysis information
  • Change analysis parameters and reanalyze the data
  • Simultaneously analyze and view data from multiple experiments
  • Save or print analyzed data for further analysis or for sharing with other laboratories that use CopyCaller® Software

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