Meet current and future guidelines

Whether you are accredited to the World Anti-Doping Agency (WADA) or one of many other global and regional governing bodies, keeping up to date on current prohibited substance screening isn’t easy.

Thermo Fisher Scientific is routinely selected to support in and out of competition testing with high-throughput instruments for screening large sets of compounds efficiently in a single methods approach, while staying ahead of future banned substances.

Featured prohibited list screening products
Featured categories

Answer your most challenging sport testing applications with our high-performance GC-MS & GC-MS/MS systems.

To ensure athletes play true, our market leading solutions help you profile athletes and confirm steroid use with the precision and sensitivity expected.

Whether you require high-throughput, highly sensitive quantitative performance or screening solutions to retrospectively answer tomorrow's doping questions, we have you covered.

Sample preparation is a key step in analytical workflow. Our solutions include a multitude of consumables and automated platforms to enable fast, reproducible and easy sample preparation—whatever your workflow requirements may be.

Confirm the presence of synthetic forms of endogenous anabolic androgenic steroids (EAAS) in urine samples.

Comprehensive screening of known and unknown performance enhancing substances is a critical part of maintaining sports true.


Typical prohibited substance screening workflows

Solve your most challenging applications with our high-performance GC-MS and LC-MS systems.

Sample preparation

Prohibited substance testing routinely screens athletes for hundreds of compounds in a number of WADA Classes. Not all hyphenated mass spectrometry workflows offer the sensitivity or performance capabilities necessary to measure the analytes of interest, laboratories utilize a variety of configurations. Starting with typically urine-based samples, laboratories will need to utilize a multi-step preparation to maximize system sensitivity.

GC-MS workflows (non-peptidic):

Hydrolysis + Extraction + Derivitization

LC-MS workflows (peptidic & non-peptidic):

Hydrolysis + Extraction

Sample preparation application handbook

Access the handbook to learn more about the variety of forensic toxicology and sport doping sample preparation options available to you.

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Screen and qualify

Sports testing laboratories rely on a variety of mass spectrometry based workflows to test for various WADA Classes of prohibited substances. Below is a comparative table of the various techniques. As technologies advance with increased performance, we continue to see a shift in platforms used.

Which mass spectrometer is right for you?

  TRACE™ 1310 Gas Chromatograph and ISQ™ LT Single Quadrupole GC-MS SystemTRACE™ 1310 Gas Chromatograph and ISQ™ LT Single Quadrupole GC-MS System TRACE™ 1310 Gas Chromatograph and TSQ™ 8000 Evo Triple Quadrupole systemTRACE™ 1310 Gas Chromatograph and TSQ™ 8000 Evo Triple Quadrupole system UltiMate™ 3000 RS HPLC systems and TSQ Quantiva™ Triple Quadrupole mass spectrometerUltiMate™ 3000 RS HPLC systems and TSQ Quantiva™ Triple Quadrupole mass spectrometer UltiMate™ 3000 RSLCnano system and Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass SpectrometerUltiMate™ 3000 RSLCnano system and Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
Targeted Screening
Quantitation
Unknown Profiling & Retrospective Screening
Typical WADA classes: S1, S3, S4, S5, S6, S7, S8 *
Typical WADA classes: SO, S2, S4.5, S9, P1, P2 *
Sample throughput Low to medium Low to medium High Medium to high
Cost $ $$ $$$ $$$
Sample prep Moderate Moderate Minimal Minimal
Dynamic range 7 logs 7 logs ≤ 6 logs ≤ 6 logs

* not all applications may require nanoHPLC


Clinical Research and Forensics Handbook

In our latest application handbook, we provide access to sports antidoping and forensic drug chemistry applications, peer reviewed references and recent technical posters for a wide range of experimental techniques, including mass spectrometry (including single quadrupole, triple quadrupole and quantitative high resolution systems), liquid chromatography and a variety of sample prep solutions.

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Featured webinar

In this webinar Dr. Alessandro Casilli, Brazilian Laboratory for Doping Control, recent advances in high resolution accurate mass (HRAM-MS) Orbitrap technology for measuring different ionization modes during the same run, and improving specificity and detection limits in sports doping control analyses.

Register to view webinar