KaryoStat Assays for Assessing Genomic Stability of PSC Lines
Verify normal karyotype of your hPSCs
The Applied Biosystems KaryoStat and KaryoStat HD Assays provide an alternative to g-banding karyotyping for pluripotent stem cell lines. The assays offer accurate genotyping (sample ID) plus whole-genome coverage for accurate detection of chromosomal abnormalities with results in 3 to 4 days. The assay includes arrays, reagents, and easy-to-use data analysis software for a cost-effective and streamlined analysis of pluripotent stem cell lines. Now researchers won't have to rely on g-banding karyotype service providers.
The KaryoStat Assays offer:
- Cost-effective and accurate detection of chromosomal abnormalities in pluripotent stem cell lines
- Karyotyping and genotyping (sample ID) with one assay
- Simple analysis tool that does not require cytogenetics expertise
- Results in 3 to 4 days
KaryoStat and KaryoStat HD Arrays are compatible with GeneChip Scanner 3000.
What is the difference between KaryoStat and KaryoStat HD Assay?
KaryoStat Assayhas a resolution similar to g-banding karyotyping and is recommended for most stem cell research applications. The KaryoStat HD Assay provides higher resolution analysis with greater than 99% sensitivity and can reliably detect 25–50 kb copy number changes across the genome at high specificity with single-nucleotide polymorphism (SNP) allelic corroboration.
|KaryoStat Assay||KaryoStat HD Assay|
|Gains||>2 Mb||>25–50 kb|
|Losses||>1 Mb||>25–50 kb|
|Absence of heterozygosity||>5 Mb||>1 Mb|