Archived formalin-fixed, paraffin-embedded (FFPE) samples offer a great opportunity for researchers to access samples with well-annotated clinical information for translational studies. However, until recently it has been a challenge to obtain high-quality genetic and genomic data from these samples due to the poor quality and quantity of the nucleic acid that can be obtained.

FFPE Solutions unlock the potential of these precious FFPE samples by providing highly accurate and quantitative results for:

Application

Starting material

Solution

Whole-transcriptome profiling

  • Extracted RNA

GeneChip Whole-Transcript Arrays and Reagents

microRNA and lncRNA analysis –

whole-genome

  • Extracted RNA

GeneChip miRNA Array and Reagents

microRNA analysis – singleplex

  • Directly from lysate

QuantiGene 2.0 miRNA Assay

RNA signature and fusion transcript validation

  • Directly from lysate

QuantiGene Plex Assay

Copy number and LOH analysis –

whole-genome

  • Extracted DNA

Affymetrix Genome-Wide Human SNP Array 6.0

Copy number, LOH, and somatic mutation analysis – whole-genome

  • Tissues or Extracted DNA

OncoScan FFPE Express 2.0 Services

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