TaqMan™ Drug Metabolism Genotyping Assays employ TaqMan 5´ nuclease chemistry for amplifying and detecting specific SNP alleles, multinucleotide polymorphisms (MNPs) and insertion/deletions (InDels). These assays detect polymorphisms in high-value DME pharmacogenetics markers, including PharmaADME core markers. The DME assay targets were derived from public databases, consortiums, and published articles.
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We offer a collection of TaqMan Drug Metabolism Genotyping Assays for pharmacogenomics applications. This product provides 2,700 unique assays to detect polymorphisms in 221 genes that code for various drug metabolism enzymes and drug transporters.

Order your TaqMan Drug Metabolism Genotyping Assays preplated into Fast or standard 96- or 384-well plates with the TaqMan Custom Plating Service. Perfect for analyzing a large number of samples for a few targets or for evaluating a few samples for a large number of targets.

Defined collections of TaqMan Assays for specific DME gene targets, including 95% of the core markers defined by the PharmaADME group.

Resources

Brochure: TaqMan Assays for genetic variation research
Quick Reference Card: TaqMan Assays for genetic variation
Index File: TaqMan Drug Metabolism Genotyping Assays
Poster: Coverage of the PharmaADME Consortium core marker list by TaqMan DME and Copy Number Assays
Application Notes: TaqMan Drug Metabolism Genotyping Assays for Triallelic SNPs
Bulletin: TaqMan Drug Metabolism Genotyping Assays
Data Sheet: TaqMan Drug Metabolism Genotyping Assays
Poster: Annotation of Polymorphisms in Drug Metabolizing Enzymes
How well do the HapMap SNPs “tag” functional variants in Drug Metabolizing Enzyme Genes?

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