Thank you for joining us at our booth to talk about your process, our solutions, and how we can help you with your bioprocessing needs. For more information on products and services highlighted at INTERPHEX 2017, please download the documents below:

Introducing the HyPerforma 5:1 2,000 L Single-Use Bioreactor (S.U.B.)

Based on mixing principles associated with stainless steel bioreactors but with all the advantages of single-use products, our new 2,000 L S.U.B. is also enabled with 5:1 turndown for lower working volumes. 

Learn about how 5:1 turndown can help you intensify seed train methods and scale-up.

Featured bioprocessing solutions:

With a broad portfolio ranging from single-use technologies to high-quality media and sera, to purification and analytics, we strive to design solutions that meet your unique challenges.

MycoSEQ Mycoplasma Detection Assay

Highly sensitive, specific, and comprehensive Mycoplasma species detection in less than 5 hours, enabling in-process monitoring during cell culture manufacturing.

Gibco GlycanTune Total Feeds

Supplements that help you achieve consistent protein quality by dialing in your specific glycan profile. 

GlycanAssure Glycan Analysis and Quantitation System

The first glycan analysis platform that combines both high throughput and high data quality in an integrated system for sample preparation and analysis (96 samples in 7–9 hours).

Acclimate Single-Use Freeze/Thaw Shipping System

Single-use BioProcess Container (BPC) and shell combination used for freezing, thawing, and shipping of biopharmaceutical fluids in commercial equipment such as walk-in freezers, coldrooms, and temperature-controlled cabinets or water baths.

Thermo Scientific POROS Ion Exchange Chromatography Resins

Our quality POROS ion exchange chromatography resins support high capacity, high resolution, and high throughput, enabling increased process flexibility and optimal manufacturing efficiency.

Whether you are trying to improve productivity through higher yields or workflow efficiencies, the result is increased capacity and reduced cost of goods. 

Finesse Smart Technology Platform A comprehensive measurement and control solution, including sensors, controllers, and software, that provides integrated intelligence and plug-and-play flexibility  to optimize the bioproduction workflow.  

Gibco Dynamis Medium

Powerful performance in a base medium to maximize titers, sustain higher cell densities, simplify reconstitution, and streamline regulatory processes—in liquid or AGT dry format.

Gibco EfficientFeed C+ (Plus) AGT Supplement

Designed for fed-batch culture of multiple cell lines to assist with process development and maximization of bioreactor utilization.

BioProcess Containers (BPCs)

Disposable single-use flexible and rigid containment systems commonly used for all types of liquid-handling applications in the biopharmaceutical and biomanufacturing industries due to their efficiencies in turnaround, cleanup, and validation.

Thermo Scientific Nunc Cell Factory System

Simple, multilayered cell culture solutions for the cultivation of adherent cells that can be scaled up to fully commercial-scale processes using an automated manipulator, CO2 incubator, and shaker.

Thermo Scientific Harvestainer Microcarrier Separation System

A single-use system for optimized separation of microcarrier beads from cells. The new solution is suitable for scale-up as well as large-scale manufacturing, with four inner bag sizes ranging from 3 L to 50 L.

Bioprocessing liquid capabilities

Ready-to-use cell culture media, media supplements, buffers, and other process liquids packaged in standard and customized bioprocess containers (BPCs) from 1 L to 1,000 L.

Thermo Scientific CaptureSelect Affinity Ligands

Highest-specificity resins for their target molecules, enabling purification of a wide range of even the most challenging therapeutic proteins, gene therapy vectors, and vaccines, with the potential to eliminate additional purification steps. 

In addition to quality raw materials, you need a robust supply chain with cGMP-compliant facilities and warehousing capabilities to support those materials.

Robust chemical sourcing

Source for fine chemical raw materials with a robust supply chain to help ensure compliance, minimize total cost of material ownership, and reduce risk of supply interruption.

Supply chain logistics and services

Supply chain services and consultation to help customers build more secure, robust, and transparent supply chains, including raw material handling, order and logistics management, QC sampling, quality management, and custom inventory.

Fluid transfer systems

Optimize your manufacturing processes with standard and custom-built, fully assembled single-use fluid transfer systems delivered in as little as 3 weeks’ time.

Integrated single-use stocking program

Preconfigured single-use mixer and integrated bioreactor systems available for factory acceptance testing (FAT) and immediate delivery to help reduce lead times and get you up and running.

With a broad portfolio ranging from single-use technologies to high-quality media and sera, to purification and analytics, we strive to design solutions that meet your unique challenges.

MycoSEQ Mycoplasma Detection Assay

Highly sensitive, specific, and comprehensive Mycoplasma species detection in less than 5 hours, enabling in-process monitoring during cell culture manufacturing.

Gibco GlycanTune Total Feeds

Supplements that help you achieve consistent protein quality by dialing in your specific glycan profile. 

GlycanAssure Glycan Analysis and Quantitation System

The first glycan analysis platform that combines both high throughput and high data quality in an integrated system for sample preparation and analysis (96 samples in 7–9 hours).

Acclimate Single-Use Freeze/Thaw Shipping System

Single-use BioProcess Container (BPC) and shell combination used for freezing, thawing, and shipping of biopharmaceutical fluids in commercial equipment such as walk-in freezers, coldrooms, and temperature-controlled cabinets or water baths.

Thermo Scientific POROS Ion Exchange Chromatography Resins

Our quality POROS ion exchange chromatography resins support high capacity, high resolution, and high throughput, enabling increased process flexibility and optimal manufacturing efficiency.

Whether you are trying to improve productivity through higher yields or workflow efficiencies, the result is increased capacity and reduced cost of goods. 

Finesse Smart Technology Platform A comprehensive measurement and control solution, including sensors, controllers, and software, that provides integrated intelligence and plug-and-play flexibility  to optimize the bioproduction workflow.  

Gibco Dynamis Medium

Powerful performance in a base medium to maximize titers, sustain higher cell densities, simplify reconstitution, and streamline regulatory processes—in liquid or AGT dry format.

Gibco EfficientFeed C+ (Plus) AGT Supplement

Designed for fed-batch culture of multiple cell lines to assist with process development and maximization of bioreactor utilization.

BioProcess Containers (BPCs)

Disposable single-use flexible and rigid containment systems commonly used for all types of liquid-handling applications in the biopharmaceutical and biomanufacturing industries due to their efficiencies in turnaround, cleanup, and validation.

Thermo Scientific Nunc Cell Factory System

Simple, multilayered cell culture solutions for the cultivation of adherent cells that can be scaled up to fully commercial-scale processes using an automated manipulator, CO2 incubator, and shaker.

Thermo Scientific Harvestainer Microcarrier Separation System

A single-use system for optimized separation of microcarrier beads from cells. The new solution is suitable for scale-up as well as large-scale manufacturing, with four inner bag sizes ranging from 3 L to 50 L.

Bioprocessing liquid capabilities

Ready-to-use cell culture media, media supplements, buffers, and other process liquids packaged in standard and customized bioprocess containers (BPCs) from 1 L to 1,000 L.

Thermo Scientific CaptureSelect Affinity Ligands

Highest-specificity resins for their target molecules, enabling purification of a wide range of even the most challenging therapeutic proteins, gene therapy vectors, and vaccines, with the potential to eliminate additional purification steps. 

In addition to quality raw materials, you need a robust supply chain with cGMP-compliant facilities and warehousing capabilities to support those materials.

Robust chemical sourcing

Source for fine chemical raw materials with a robust supply chain to help ensure compliance, minimize total cost of material ownership, and reduce risk of supply interruption.

Supply chain logistics and services

Supply chain services and consultation to help customers build more secure, robust, and transparent supply chains, including raw material handling, order and logistics management, QC sampling, quality management, and custom inventory.

Fluid transfer systems

Optimize your manufacturing processes with standard and custom-built, fully assembled single-use fluid transfer systems delivered in as little as 3 weeks’ time.

Integrated single-use stocking program

Preconfigured single-use mixer and integrated bioreactor systems available for factory acceptance testing (FAT) and immediate delivery to help reduce lead times and get you up and running.

Technical presentation:

Improving Single-Use Bioreactor Design and Process Development—New Research Towards Intensifying Seed-Train and Scale-up Methods Using 5:1 Turn-Down

Speaker: Nephi Jones, R&D Manager, Advanced Technology, Thermo Fisher Scientific
Date:  Thursday, March 23, 2017
Time: 10:30–11:15 a.m.
Location: Meeting Room 4

Download the speaker presentation:

 Improving Single-use Bioreactor design and process development using 5:1 turn-down

For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals.