Invitrogen TRIzol products are referenced in thousands of journal publications, reflecting the trust that molecular biologists have placed in TRIzol Reagent to deliver high-quality, intact RNA from many kinds of biological materials.

TRIzol reagents are offered in several ready-to-use formats. The individual products within the TRIzol reagent family are tailored to isolate total RNA or to simultaneously isolate RNA, DNA, and protein from diverse biological sources, including samples of human, animal, plant, yeast, bacterial, and viral origin.

Meet a great match for TRIzol reagents: Phasemaker Tubes

Using TRIzol reagents just got simpler, thanks to a new best friend. Invitrogen Phasemaker Tubes create a tight, durable seal between the aqueous and organic phase of your TRIzol mix. Phasemaker Tubes don’t compromise the performance of TRIzol reagents, allowing you to easily pipette off the RNA phase. It’s almost too easy.

Save money by purchasing Phasemaker Tubes together with TRIzol, TRIzol LS, or TRIzol Plus reagents, or use them with your existing TRIzol reagent.

The benefits of using Phasemaker Tubes include:

  • Higher yield—increase recovery by as much as 30%
  • Ease of use—simply use with TRIzol mix, centrifuge, and then easily pipette off the aqueous phase
  • Ready-to-use convenience—comes predispensed in 2 mL tubes
  • Increased throughput—stable gel seal allows you to maximize the number of samples per run without losing phase separation

RNA extraction product selection guide

Product Description Primary sample type
Phasemaker Tubes Creates a tight, durable seal between the aqueous and organic phase of your TRIzol mix, allowing the RNA to be easily removed and maintaining TRIzol reagent's performance All sample types processed using any TRIzol reagent
Invitrogen TRIzol Plus RNA Purification System Offers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column All sample types, especially difficult samples, including fibrous or fatty tissues and plant material
TRIzol Reagent Isolates total RNA from tissues or cells, including lipid-rich and difficult samples Tissues and cells
Invitrogen TRIzol LS Reagent Designed for use with liquid samples, such as serum or virus preparations Fluid samples such as serum and virus preparations
Invitrogen TRIzol Max Bacterial RNA Isolation Kit with TRIzol Reagent and Invitrogen Max Bacterial Enhancement Reagent Kit-based system designed to isolate total RNA from bacterial cells Bacterial samples

Featured videos

TRIzol's new best friend: Phasemaker Tubes

Phasemaker Tubes create a durable seal between the aqueous and organic phases, allowing researchers to easily pipette off the RNA phase.

How to isolate RNA from tissue or cells

Learn how to isolate ultrapure total RNA within an hour, even from difficult samples with the TRIzol Plus RNA
Purification Kit.

NEW   Nucleic Acid Purification and Analysis Support Center
Find tips, troubleshooting help, and resources for your nucleic acid purification & analysis applications.