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ERBB4 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag

Catalog number: 10363H03H50

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Description

V-erb-a erythroblastic leukemia viral oncogene homolog 4 (ERBB4), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Pro 651) of human ERBB4 precursor (NP_001036064.1) fused to the His-tagged Fc region of human IgG1 at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA. Immobilized human ERBB3-Fc at 1 µg/well can bind biotinylated recombinant human NRG1 with a linear range of 0.032-0.16 µg/ml.

Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by SINO Biological.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Purity: ≥ 85% by SDS-PAGE
Gene ID: 2066
Species: Human
Expression: Mammalian
Gene Symbol: ERBB4
Gene Aliases: HER4, MGC138404, p180erbB4, ERBB4
Product Size: 50 µg
Protein Form: Truncated, Recombinant, Cell Surface Protein
Kinase Family: EGF Receptor (ErbB) Kinase Family
Protein Family: Growth Factors & Receptors
Endotoxin Level: < 1 EU/µg
Protein Subtype: Growth Factor Receptors, Receptor Tyrosine Kinases
Molecular Weight: 97.5 kDa
Research Category: Signal Transduction, Cardiovascular Research, Oncology, Stem Cell Research
Protein Tag or Fusion: His Tag, IgG1 Fc Tag
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols

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