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FGFR4, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag

Catalog number: 10538H03H250

 Related applications: Protein Assays and Analysis

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Description

Fibroblast Growth Factor Receptor 4 (FGFR4), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Asp 369) of human FGFR4 (NP_002002.3) precursor fused to the C-terminal polyhistidine tagged Fc region of human IgG1 at the C-terminus.

Activity: Measured by its ability to inhibit FGF acidic dependent proliferation of Balb3T3 mouse fibroblasts. The ED50 for this effect is typically 2-6 ng/ml.

Formulation:140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Purity: ≥ 85% by SDS-PAGE
Gene ID: 2264
Species: Human
Expression: Mammalian
Gene Symbol: FGFR4
Gene Aliases: FGFR4, CD334, JTK2, MGC20292, TKF
Product Size: 5 x 50 µg
Protein Form: Truncated, Recombinant
Purification: PAGE
Protein Family: Cytokines & Receptors
Endotoxin Level: < 1 EU/µg
Molecular Weight: 66 kDa
Research Category: Immunology, Neurobiology, Signal Transduction, Cardiovascular Research, Stem Cell Research, Oncology
Protein Tag or Fusion: hIgG1-Fc His
Validated Application: Assay Standard

Contents & storage

Includes 5 vial of protein in suspension buffer. Store at -5 to -30°C.

Documents

Manuals & protocols