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CD63 Recombinant Human Protein, His Tag

Catalog number: 11271H08H5

 Related applications: Protein Assays and Analysis

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Description

Manufactured by Sino Biological (China); Distributed by Life Technologies.

Cluster of Differentiation 63 (CD63) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant human protein is expressed from a DNA sequence encoding the second the extracellular domain (Ala 103-Val 203) of human CD63 (P08962-1) fused to both a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.

Activity: this recombinant protein has not been tested.

Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Background
CD63, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family. Tetraspanins participate in a variety of cellular processes, likecell activation, adhesion, differentiation and tumour invasion. CD63 / Tspan-30 is expressed in melanoma and appears to be involved in regulation of motility and adhesion of melanoma cells. CD63 / Tspan-30 is associated with early stages of melanoma tumor progression. It may play a role in growth regulation. Lack of expression of CD63 in platelets has been observed in a patient with Hermansky-Pudlak syndrome (HPS). which is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects.

You may also be interested in the following CD63 products:
Organell Isolation
Primary Antibodies
Gene Expression Assays
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Purity: ≥ 90% by SDS-PAGE
Gene ID: 967
Species: Human
Expression: Mammalian
Gene Symbol: CD63
Gene Aliases: LAMP-3, ME491, MLA1, OMA81H, TSPAN30
Product Size: 5 µg
Protein Form: Truncated, Recombinant, Cell Surface Protein
Protein Family: CD Proteins
Endotoxin Level: < 1 EU/µg
Protein Subtype: Glycoproteins
Molecular Weight: 13 kDa
Research Category: Immunology, Oncology, Genetic Diseases, Signal Transduction
Protein Tag or Fusion: His Tag
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols