Fibrillarin / Nop1p Antibody (38F3)

Catalog number: 480009

Invitrogen™  Related applications: Cellular Imaging | Protein Assays and Analysis

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Description

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human, Rat, Drosophila
Validated Application: Western Blot, Immunofluorescence
Host Species: Mouse
SubClass (Isotype): IgG
Clonality: Monoclonal
Clone ID: 38F3
Antibody Fragment: Whole Antibody
Target Gene: FLB
Gene ID: 46234, 2091, 292747
Gene Symbol: FLB
Label or Dye: Unconjugated
Purification: Partially Purified
Form: Frozen
For Use With (Equipment): Fluorescence Microscope
Product Size: 100 µL
Volume (Metric): 100 µl
Shipping Condition: Wet Ice

Contents & storage

2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.

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