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IL6ST Recombinant Mouse Protein (hIgG1-Fc.His Tag, CHO expressed)

Catalog number: 50135M03C25

 Related applications: Protein Assays and Analysis

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Description

Interleukin 6 signal transducer (IL6ST), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 617) of mouse IL6ST (NP_034690.3) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Activity: Measured by its ability to inhibit the IL6R enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168). The ED50 for this effect is typically 0.03-0.1 µg/mlin the presence of 50 ng/mlrecombinant human IL6R and 100 ng/mlrecombinant human IL6.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Endotoxin Level: < 1 EU/µg
Expression: Mammalian
Form: Lyophilized
Gene Aliases: Il6st, 5133400A03Rik, AA389424, BB405851, CD130, gp130
Gene ID: 16195
Gene Symbol: IL6ST
Molecular Weight: 94.7 kDa
Product Size: 5 x 5 µg
Protein Family: CD Proteins, Cytokines & Receptors
Protein Form: Recombinant, Truncated
Protein Subtype: Cytokine Receptors, Interleukins
Protein Tag or Fusion: His Tag, IgG1 Fc Tag
Purity: ≥ 90% by SDS-PAGE
Research Category: Immunology, Oncology, Signal Transduction
Species: Mouse
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols

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