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IL6ST Recombinant Mouse Protein, His Tag

Catalog number: 50135M08H250

 Related applications: Protein Assays and Analysis

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Description

Interleukin 6 signal transducer (IL6ST), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the mouse extracellular domain (Met 1-Glu 617) of IL6ST (NP_034690.3) fused to a polyhistidine tag at the C-terminus.

Activity:
1. Measured by its ability to bind mouse IL11RA in a functional ELISA.
2. Measured by its ability to inhibit the IL6R enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168). The ED50 for this effect is typically 0.2-0.8 µg/mlin the presence of 50 ng/mlrecombinant human IL6sR and 100 ng/mlrecombinant human IL6.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Purity: ≥ 90% by SDS-PAGE
Gene ID: 16195
Species: Mouse
Expression: Mammalian
Gene Symbol: Il6st
Gene Aliases: Il6st, 5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
Product Size: 5 x 50 µg
Protein Form: Truncated, Recombinant
Protein Family: Cytokines & Receptors, CD Proteins
Endotoxin Level: < 1 EU/µg
Protein Subtype: Interleukins, Cytokine Receptors
Molecular Weight: 68 kDa
Research Category: Immunology, Oncology, Signal Transduction
Protein Tag or Fusion: His Tag
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols