CD62P / P-selectin Antibody (3H20L10), ABfinity™ Rabbit Monoclonal

Catalog number: 701257

Invitrogen™  Related applications: Cellular Imaging | Flow Cytometry | Protein Assays and Analysis

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Description

This antibody is predicted to react with mouse, rat and non-human primate based on sequence homology.

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale, and purified with Protein A.

ABfinity™ monoclonal antibodies resemble rabbit monoclonals isolated from serum or produced by hybridomas, but demonstrate greater specificity and sensitivity. Because ABfinity™ recombinant antibodies are derived from cloned DNA sequences of the heavy and light antibody chains, they are not susceptible to cell-line drift or lot-to-lot variation, thus allowing for peak specificity and performance.

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.



P-selectin is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human
Validated Application: Flow Cytometry, Western Blot, Immunofluorescence
Host Species: Rabbit
SubClass (Isotype): IgG
Clonality: Monoclonal
Clone ID: 3H20L10
Antibody Fragment: Whole Antibody
Target Gene: P-Selectin
Gene ID: 6403
Gene Symbol: SELP
Label or Dye: Unconjugated
Purification: Affinity Purified
Concentration: 0.5 mg⁄ml
Form: Liquid
Product Size: 100 µg
Volume (Metric): 200 µl
Shipping Condition: Wet Ice

Contents & storage

2 - 8 °C for up to 1 month, -20 °C for long storage.

Avoid repeated freezing and thawing.

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