Vitronectin (VTN-N) Recombinant Human Protein, Truncated

Catalog number: A14700

Gibco™  Related applications: Clinical & Translational Research | Stem Cell Culture | Stem Cell Engineering & Reprogramming

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Description

Vitronectin (VTN-N) is a recombinant human protein that provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). When used with Essential 8™ Medium (A1517001), vitronectin (VTN-N) has been proven to maintain pluripotency and normal growth characteristics in multiple PSC lines. In addition, vitronectin (VTN-N) has been shown to support PSC growth for >50 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages. As published by Guokai Chen et al. (1) in the laboratory of James Thomson, the VTN-N variant of vitronectin supports human pluripotent stem cell attachment and survival better than wild-type vitronectin when used in conjunction with Essential 8™ Medium.

Vitronectin (VTN-N) is:

Optimized—designed in the laboratory of James Thomson for use with Essential 8™ Medium
Defined—for reduced variability in your PSC cultures
Cost effective—for economical and scalable PSC culture

Optimized and Defined Surface
Unlike standard basement membrane extracts (BMEs), vitronectin (VTN-N) was designed in the laboratory of James Thomson for use with Essential 8™ Medium and has been shown to support human pluripotent stem cell attachment and survival better than wild type vitronectin. Vitronectin (VTN-N) provides an optimal environment for feeder-free pluripotent stem cell culture.

Reduce Variability
Vitronectin (VTN-N) is a defined, recombinant human protein that reduces variability in your PSC cultures compared to human-plasma derived vitronectin and standard basement membrane extracts (BMEs).

Cost Effective
When used with Essential 8™ Medium, vitronectin (VTN-N) provides a cost effective, defined system for feeder free culture of human pluripotent stem cells (PSCs).

Commercialized in Partnership with Cellular Dynamics International.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Species: Human
Protein Subtype: Vitronectin
Research Category: Stem Cell Research
Purity: 95 %
Product Size: 1 mL
Purification: HPLC
Concentration: 500 µg⁄ml
Endotoxin Level: Very Low

Contents & storage

Store at -80°C.

Documents

Manuals & protocols

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