CD21 / CR2 Antibody (7E9), Pacific Blue™ conjugate, Molecular Probes™

Catalog number: A14923

Invitrogen™  Related applications: Flow Cytometry

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Description

CD21, also known as CR2, C3d receptor and EBV receptor), is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Mouse
Validated Application: Flow Cytometry
Host Species: Rat
SubClass (Isotype): IgG2a
Clonality: Monoclonal
Clone ID: 7E9
Antibody Fragment: Whole Antibody
Target Gene: CD21/CD35
Gene ID: 12902
Gene Symbol: Cr2
Accession Number: P19070
Gene Aliases: Cr1, C3DR, CD21, CD35, Cr-1, Cr-2
Label or Dye: Pacific Blue™
Excitation⁄Emission (nm): 405⁄455
Concentration: 0.5 mg⁄ml
Form: Liquid
Number of Reactions: 25 Tests
For Use With (Equipment): Flow Cytometer, Attune® Acoustic Focusing Cytometer
Product Size: 25 µg
Other Additives: Sodium Azide Preservative
Shipping Condition: Wet Ice

Contents & storage

Store at 2-8°C

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