CD14 Antibody (61D3), APC-Cy7® conjugate, Molecular Probes™

Catalog number: A15453

Invitrogen™  Related applications: Flow Cytometry

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Description

CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human
Validated Application: Flow Cytometry
Host Species: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Clone ID: 61D3
Antibody Fragment: Whole Antibody
Target Gene: CD14
Gene ID: 929
Gene Symbol: CD14
Gene Aliases: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
Label or Dye: APC-Cy®7
Excitation⁄Emission (nm): 600-650⁄767
Excitation Class: near IR
Concentration: 0.1 mg⁄ml
Form: Liquid
Number of Reactions: 100 Tests
For Use With (Equipment): Attune® Acoustic Focusing Cytometer
Product Size: 100 µg
Protein Family: CD Proteins
Research Category: Immunology
Other Additives: Sodium Azide Preservative

Contents & storage

Store in refrigerator (2–8°C).

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