PDGF-RA / CD140a Antibody (APA5), PE conjugate, Molecular Probes™

Catalog number: A18351

Invitrogen™  Related applications: Flow Cytometry

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Description

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Mouse
Validated Application: Flow Cytometry
Host Species: Rat
SubClass (Isotype): IgG2a, kappa
Clonality: Monoclonal
Clone ID: APA5
Antibody Fragment: Whole Antibody
Target Gene: CD140a
Gene ID: 18595
Gene Symbol: Pdgfra
Gene Aliases: CD140a, Pdgfr-2, AI115593
Label or Dye: R-PE
Excitation⁄Emission (nm): 496⁄578
Excitation Class: Visible
Concentration: 0.2 mg⁄ml
Form: Liquid
Number of Reactions: 100 Tests
For Use With (Equipment): Attune® Acoustic Focusing Cytometer
Product Size: 50 µg
Other Additives: Sodium Azide Preservative

Contents & storage

Store in refrigerator (2–8°C).

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Manuals & protocols

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