TNF CTS™ Recombinant Human Protein

Catalog number: CTP3011

Gibco™  Related applications: Mammalian Cell Culture | Primary Cell Culture | Stem Cell Culture

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Description

Recombinant TNF is a bioactive protein intended for use in cell culture applications. TNF causes cytolysis and cytostasis of many tumor cell lines. TNF has a wide spectrum of activities, including chemotaxis of neutrophils, alteration of the endothelium, inhibition of anticoagulatory mechanisms, and promotion of angiogenesis. ED50 range = 0.02 to 0.05 ng⁄mL (Specific Activity: 2 x 10^7 to 5 x 10^7 units⁄mg), determined by the dose dependent cytotoxic effect on L929 cells in the presence of actinomycin D.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Activity: 0.013 ng/ml
Bioassay: Cytotoxicity of L929 cells
Endotoxin Level: < 0.1 ng/µg
Expression: E. coli
Gene Aliases: TNF-α
Molecular Weight: 17.5 kDa
Product Size: 100 µg
Protein Family: Cytokines & Receptors
Protein Form: Ligand, Recombinant
Protein Subtype: TNF (Tumor Necrosis Factor)
Purification: Gel-Purified
Purity: 95 %
Purity or Quality Grade: Carrier-Free
Reactivity: Human
Research Category: Clinical Research, Immunology, Inflammation, Oncology, Signal Transduction, Stem Cell Research
Species: Human
Validated Application: Cell Culture
Shipping Condition: Wet Ice

Contents & storage

Lyophilized protein can be stored at 2-8°C dessicated. Once reconstituted, store in aliquots at ≤20°C. Avoid multiple freeze⁄thaw cycles.

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