CD4 Antibody (S3.5), PerCP conjugate, Molecular Probes™

Catalog number: MHCD0431

Invitrogen™  Related applications: Flow Cytometry

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Description

PerCP conjugates are excited by the 488 nm line of the argon-ion laser and have a large Stokes shift, providing minimal spectral overlap into the R-PE (phycoerythrin) channel.

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein-1 (pgp-1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non-hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Specifications

Reactivity: Human
Validated Application: Flow Cytometry
Host Species: Mouse
SubClass (Isotype): IgG2a
Clonality: Monoclonal
Clone ID: S3.5
Antibody Fragment: Whole Antibody
Target Gene: CD4
Gene ID: 920
Gene Symbol: CD4
Label or Dye: PerCP
Excitation⁄Emission (nm): 488⁄678
Form: Liquid
Neutralizing Antibody: No
Number of Reactions: 100 Tests
For Use With (Equipment): Flow Cytometer
Product Size: 0.5 ml
Buffer: PBS (Phosphate-Buffered Saline)
Comments: For use on any flow cytometer with a blue laser.
Other Additives: BSA Stabilizer (Highly Purified Grade)
Shipping Condition: Wet Ice

Contents & storage

CD4, Mouse anti-human ,(PerCP), 0.5 mL in PBS with 0.1% sodium azide. Store reagents at 2-8°C.

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