IL33 Recombinant Human Protein

Catalog number: PHC9253

Gibco™  Related applications: Mammalian Cell Culture

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Description

Recombinant IL33 is a bioactive protein intended for use in cell culture applications. IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NF-κB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Mass: 1 mg
Purity: 95 %
Gene ID: 90865
Species: Human
Bioassay: Proliferation of Mouse D10S Cells
Expression: E. coli
Reactivity: Human
Gene Symbol: IL33
Gene Aliases: IL-33
Product Size: 1 mg
Protein Form: Recombinant, Ligand
Purification: Sequential Chromatography
Protein Family: Cytokines & Receptors
Endotoxin Level: < 0.1 ng/µg
Protein Subtype: Interleukins
Accession Number: NM_033439
Molecular Weight: 18 kDa
Research Category: Signal Transduction, Cell Cycle & Proliferation
Specific Activity: 1.0 x 107 - 1.0 x 106 units⁄mg
Biological Activity: ED50 range = 0.1-1.0 ng⁄mL
Validated Application: Cell Culture
Purity or Quality Grade: Carrier-Free
Protein Length or Portion (a.a.): 159 aa
Shipping Condition: Wet Ice

Contents & storage

Lyophilized Human IL-33 should be stored at 2-8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ –20°C (not in a frost-free freezer). Keep freeze-thaw cycles to a minimum.
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