Frizzled 7 Recombinant Human Protein

Catalog number: PHC9474

Gibco™  Related applications: Cell Viability, Proliferation & Function | Mammalian Cell Culture

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Description

Recombinant Human Frizzled-7 (FZD7) is a bioactive recombinant protein intended for use in cell culture applications. FZD7 is a member of the Frizzled family, which are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Wnt signaling is involved in several developmental processes.

The protein sequence of Frizzled-7 corresponds to the extracellular region of mature Human Frizzled 7, aa 33-185, fused to the Fc region of Human IgG1.

The equilibrium binding constant, KD, of Human Frizzled 7 was measured at less than 10nM using mouse Wnt3a as the ligand. Measurements were made using the ForteBio Octet optical biosensor instrument.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Mass: 10 µg
Purity: >95 %
Species: Human
Expression: Mammalian
Product Size: 10 µg
Protein Form: Recombinant
Purification: Sequential Chromatography
Endotoxin Level: < 0.1 ng/µg
Protein Subtype: Wnt Proteins & Receptors
Molecular Weight: 98 kDa
Research Category: Signal Transduction, Development
Biological Activity: KD = <10 nM
Validated Application: Cell Culture
Purity or Quality Grade: Carrier-Free
Protein Length or Portion (a.a.): aa 33-185
Shipping Condition: Wet Ice

Contents & storage

Store this lyophilized preparation at 2 to 8°C. Upon reconstitution, apportion into working aliquots and store at ≤ –20°C. Avoid repeated freeze⁄thaw cycles.

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