TPO (Thrombopoietin), Recombinant Human Protein

Catalog number:  PHC9513

 Related applications: Cell Viability, Proliferation & Function | Mammalian Cell Culture | Stem Cell Culture

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Recombinant Human Thrombopoietin (TPO) is a bioactive protein intended for use in cell culture applications. TPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, which is the product of the myeloproliferative leukemia virus oncogene. Recombinant Human Thrombopoeitin (TPO) is one of the many GIBCO® recombinant bioactive proteins available from Life Technologies. This is the 10 milligram size.

High purity—minimal interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—GIBCO® proteins bioassayed with GIBCO® media

High purity recombinant bioactive protein
Recombinant Human Thrombopoietin (TPO) is one of more than 250 GIBCO® recombinant proteins available from Life Technologies. To help ensure GIBCO® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High biological activity
In-house activity testing of Recombinant Human Thrombopoeitin (TPO) includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Thrombopoietin (TPO) specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Proven compatibility
GIBCO® proteins are bioassayed with GIBCO® media. Since 1962, GIBCO® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

We also offer a selection of growth factors for use in cell therapy applications through our GIBCO® Cell Therapy Systems (CTS™) product line.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Related links
See our selection of recombinant GIBCO® growth factors.
Learn more about the GIBCO® Cell Therapy Systems (CTS™) product line.
For Research Use Only. Not for use in diagnostic procedures.


Research Category: Angiogenesis, Endocrinology, Stem Cell Research
Activity: 0.5 ng/ml
Bioassay: Proliferation of TF1 cells
Endotoxin Level: < 1 EU/ml
Expression: Mammalian
Gene Aliases: TPO (Thrombopoietin)
Molecular Weight: 85 kDa
Product Line: Gibco®
Product Size: 1 mg
Protein Family: Growth Factors & Receptors
Protein Form: Ligand, Recombinant
Protein Length or Portion (a.a.): 332 aa
Protein Subtype: TPO
Purification: Gel-Purified
Purity: 90 %
Purity or Quality Grade: Carrier-Free
Species: Human
Validated Application: Cell Culture
Shipping Condition: Dry Ice

Contents & storage

Store in freezer (-5 to -30°C).


Manuals & protocols