Soluble TNF-RII Recombinant Human Protein

Catalog number: PHR3025

Gibco™  Related applications: Cell Viability, Proliferation & Function | Mammalian Cell Culture

Error loading your content!

  Catalog number
Select a plan
Unit size
List price ({{currency}}) Your price ({{currency}}) Availability Qty
{{product.sku}} {{product.sku}}
also known as {{product.formattedSku}} 
{{subscriptionDetails.selectedRatePlan.billingPeriod}} {{subscriptionDetails.selectedRatePlan.billingPeriod}} {{product.availability.message}}
Pro add-ons

Your on-site stock

›› {{supplyCenter.scName}}({{scProduct.stockOnHand}} In stock)
›› {{supplyCenter.scName}}(Out of stock)
›› {{supplyCenter.scName}}
This item is not currently available on-site. Depending on your Supply Center settings you may be able to add the item to cart above else use the Order Non-Stocked Items' tab on the Supply Center home page.
Back to top

Description

Recombinant Soluble TNF-RII is a bioactive protein intended for use in cell culture applications. sTNF-RII is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Lyophilized
Mass: 20 µg
Purity: 98 %
Gene ID: 7133
Species: Human
Expression: E. coli
Gene Aliases: Soluble TNF-RII
Product Size: 20 µg
Protein Form: Recombinant, Ligand
Purification: Sequential Chromatography
Protein Family: Cytokines & Receptors
Endotoxin Level: < 0.1 ng/µg
Protein Subtype: TNF (Tumor Necrosis Factor)
Molecular Weight: 18.9 kDa
Research Category: Immunology, Signal Transduction, Inflammation, Oncology
Validated Application: Cell Culture
Shipping Condition: Approved for shipment on Wet or Dry Ice

Contents & storage

Store in freezer (-5 to -30°C).

Documents

Manuals & protocols

Recommended products