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CHEK2 (CHK2) Recombinant Human Protein

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Description

CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_009125
Gene Aliases: CHEK2 (CHK2)
Gene ID: 11200
Kinase Group: Ser⁄Thr Kinases: CAMK Group
Molecular Weight: 66 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Research Category: DNA Replication & Repair, Oncology, Signal Transduction
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Omnia® Bulk Substrate, Z'-LYTE™
Target Gene: CHK2 checkpoint homolog
Validated Application: Kinase Assay
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: RAD53 Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.04% Triton X-100, 4mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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