LanthaScreen® Tb-IKBa pSer32 Antibody Kit

Catalog number: PV3563

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.

For use in combination with the Fluorescein-IKK peptide substrate (PV3507) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Format: 384-well plate
Gene ID: 1147, 2869, 3551
Readout: End Point
Technique: TR-FRET
Reactivity: Human
Label or Dye: Tb (Terbium), FITC (Fluorescein)
Product Size: 1 mg
Target Enzyme: Serine⁄Threonine Kinases
Validated Kinases: CHUK, GRK5, GRK6, IKBKB, IKBKE
Antibody Molecular Weight: 150000 Da
Excitation⁄Emission (nm): 340⁄490, 520
Shipping Condition: Dry Ice

Contents & storage

Terbium-labeled anti-IkappaBalpha [pSer32] antibody in HEPES buffered saline. Store at -20°C.

Documents

Manuals & protocols