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MET [M1250T] Recombinant Human Protein

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Description

MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_000236.2, M1250T
Gene Aliases: MET M1250T
Gene ID: 4233, 4790
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Molecular Weight: 53.7 kDa
Product Size: 10 µg
Protein Length or Portion (a.a.): aa 956-1390; M1250T
Protein Subtype: Receptor Tyrosine Kinases
Protein Tag or Fusion: His Tag
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Omnia® Bulk Substrate, Z'-LYTE™
Tag Position: N-Terminal
Target Gene: met proto-oncogene
Validated Application: Kinase Assay
Expression: Baculovirus
Kinase Family: MET (HGFR) Kinase Family
Protein Form: Cytoplasmic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols