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MET [M1250T] Recombinant Human Protein

Catalog number: PV3968

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Mass: 10 µg
Gene ID: 4233, 4790
Species: Human
Target Gene: met proto-oncogene
Gene Aliases: MET M1250T
Kinase Group: Tyrosine Kinases
Product Size: 10 µg
Tag Position: N-Terminal
Protein Family: Kinases & Inhibitors
Protein Subtype: Receptor Tyrosine Kinases
Accession Number: NP_000236.2, M1250T
Molecular Weight: 53.7 kDa
Research Category: Signal Transduction
System Compatibility: LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate, LanthaScreen® Antibody
Protein Tag or Fusion: His Tag
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 956-1390; M1250T
Expression: Baculovirus
Kinase Family: MET (HGFR) Kinase Family
Protein Form: Recombinant, Cytoplasmic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols