LanthaScreen® Tb-anti-phospho-p53 [pSer15] Antibody Kit

Catalog number: PV5131

 Related applications: Oncology & Genetic Disease Research | Target & Lead Identification & Validation

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Description

The p53 tumor suppressor protein is an essential component of many different signaling pathways. The LanthaScreen® antibody detects the phosphorylation of p53 at Ser15 by a range of kinases including DNA-PK, ATM, and ATR.

For use in combination with the Fluorescein-p53 (Ser15) peptide substrate (PV5132) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Format: 384-well plate
Readout: End Point
Technique: TR-FRET
Reactivity: Human
Label or Dye: Tb (Terbium), FITC (Fluorescein)
Product Size: 1 mg
Target Enzyme: Serine⁄Threonine Kinases
Antibody Molecular Weight: 150000 Da
Excitation⁄Emission (nm): 340⁄490, 520
Shipping Condition: Dry Ice

Contents & storage

Terbium-labeled anti-phospho-p53 [pSer15] antibody in HEPES buffered saline. Store at -20°C.

Documents

Manuals & protocols