Apolipoprotein A-V

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  • Citations (1)

General Description

Research indicates that genetic variations are key for understanding the genetic basis of complex traits and diseases. Variants can influence phenotypes, the susceptibility of an individual to disease, drug response and human genome evolution. Many SNPs have been associated with common disorders such as diabetes, obesity, and cardiovascular diseases. Further research into identifying the risk factors and understanding the biology of risk variants would enable a more complete view of these conditions and lead to improved disease treatment and prevention.


Studies show that APOA5 takes part in the metabolism of the triglicerides, accelerating the catalysis of the LDL and the activation of proteín lipase. Research studies have show that the presence of allele C at position 1131 is related to an increase of risk of cardiovascular disease.

Target Disease/Application

Apolipoprotein A-V

Assay ID Clinical Name Gene Symbol Gene Name dbSNP ID  
C___2310403_10 APOA5 1131T>C APOA5 Apolipoprotein A-V rs662799


General Specifications

# of assays: 1
Technology: TaqMan® Assays
Scale: Available in multiple scales
Intended Use: Research Use Only

Contents and Storage

-20° C


Citations & References (1)

  • The 1131T3C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men.

Yangsoo Jang,Y et al.
Am J Clin Nutr (2004) 80:832–40.