Coagulation Factor II (Thrombin)

  • Product Reviews (0)
  • Citations (1)

General Description

Research indicates that genetic variations are key for understanding the genetic basis of complex traits and diseases. Variants can influence phenotypes, the susceptibility of an individual to disease, drug response and human genome evolution. Many SNPs have been associated with common disorders such as diabetes, obesity, and cardiovascular diseases. Further research into identifying the risk factors and understanding the biology of risk variants would enable a more complete view of these conditions and lead to improved disease treatment and prevention.


Research shows that the condition known as prothrombin 20210 is associated with a G-to-A mutation of the prothrombin gene. Individuals with the condition tend to have higher prothrombin levels.

Target Disease/Application

Coagulation Factor II (Thrombin)

Assay ID Clinical Name Gene Symbol Gene Name dbSNP ID  
C___8726802_20 Prothrom G20210A-factor II FII Coagulation Factor II (Thrombin) rs1799963


General Specifications

# of assays: 1
Technology: TaqMan® Assays
Scale: Available in multiple scales
Intended Use: Research Use Only

Contents and Storage

-20° C


Citations & References (1)

  • Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review.

Segal JB, Brotman DJ, Necochea AJ, Emadi A, Samal L, Wilson LM, Crim MT, Bass EB.
JAMA. (2009) 17:2472-85.