Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-32444 detects LRRK2 from bovine, human samples.
PA1-32444 has been successfully used in immunofluorescence, Western blot applications.
The PA1-32444 immunogen is: A C-terminal synthetic peptide made to the human LRRK2 protein sequence (between residues 2500-2527).
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: augmented in rheumatoid arthritis 17; BC 300-268; Dardarin; DKFZp434H2111; FLJ45829; leucine-rich repeat kinase 2; Leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; LRRK-2
Gene Aliases: LRRK2; PARK8
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