Genomics and proteomics search results

IKBKB (IKK Beta) Recombinant Human Protein

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex. ...

Specifications

Gene ID
3551, 4088
Species
Human
Target Gene
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Aliases
IKBKB (IKK Beta)
Kinase Group
Ser⁄Thr Kinases: Other
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_001547
Molecular Weight
114 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
Z'-LYTE™
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3836
7e294a1f372c861cc5718c4245eab356_CmgtBuyProduct

CellSensor® NFkB-bla ME-180 Cell Line

The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells. The cell line was created through fluorescence activated cell sorting (FACS) of cells respons ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Cytokines
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1667
ec85931a0d98842c1c02ba3af27e5f11_CmgtBuyProduct

Pierce™ IKBKB Antibody (10A2) (Thermo Scientific™)

MA5-15319 targets IKBKB in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515319
c018714220e5027ab307272f659a6b9e_CmgtBuyProduct

Pierce™ IKBKB Antibody (10A2C5B3) (Thermo Scientific™)

MA5-15320 targets IKBKB in IHC and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515320
62a2befbb79f24e63109dce2a0c793fa_CmgtBuyProduct

Pierce™ NIBP Antibody (Thermo Scientific™)

NIBP is a 1246 amino acid intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its neuronal expression ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA523130
0d9dc2f1f0a31b89fc2f338bb726bbdb_CmgtBuyProduct

Pierce™ IKK-beta Antibody (10AG2) (Thermo Scientific™)

Suggested positive control: Daudi, HeLa, NIH-3T3. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516154
6d042ebf7c43e3dc95ee1461f3c48bf3_CmgtBuyProduct

Pierce™ IKK-beta / IKK2 Antibody (10A9B6) (Thermo Scientific™)

Suggested positive control: Daudi, HeLa, Jurkat, or NIH-3T3. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516162
df8497632ec570747cc50ba613a88836_CmgtBuyProduct

Pierce™ IKK beta Antibody (Thermo Scientific™)

In Western blot applications, this antibody detects a band at ~87kDa. A suggested positive control is Jurkat cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519916
9f843fc1f0e0224621013ca08db43808_CmgtBuyProduct

Pierce™ Phospho-IKK-alpha pSer176 + IKK-beta pSer177 Antibody (J.10.3) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514857
500c467311442ebc333f38ce5c0bf14f_CmgtBuyProduct

Pierce™ Phospho-IKK pSer176 + pSer180 Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517593
5b1efe17bb9123cc14bdc557911a1e64_CmgtBuyProduct

Pierce™ IKK-beta Antibody (J.414.5) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515080
2fcc84bba8ff2a71a5a50938b027dae5_CmgtBuyProduct

Pierce™ IKK-beta Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517804
41ade41098388b899e8ca47ba0758f97_CmgtBuyProduct

Pierce™ IKK beta Antibody (Thermo Scientific™)

PA5-21683 targets IKK beta in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA521683
bffce33401f96d106756f5284c06c077_CmgtBuyProduct

MAP3K14 (NIK) Recombinant Human Protein

MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes. ...

Specifications

Gene ID
9020
Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 14
Gene Aliases
MAP3K14 (NIK)
Kinase Group
Ser⁄Thr Kinases: STE Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_003945.2
Molecular Weight
96.9 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 318-947
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
STE Unique Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4902
6a27de3a8b8ec97d7b5c31c151bc3514_CmgtBuyProduct

Pierce™ IKK beta Antibody (62AT216) (Thermo Scientific™)

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA511177
a13764306cc9e5c38175b8bf04f03dc8_CmgtBuyProduct