Genomics and proteomics search results

Novex™ MDM2 Antibody (IF2) (Novex™)

MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inacti ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Immunoprecipitation
Immunofluorescence
Host
Mouse
Clonality
Monoclonal
Clone ID
IF2
Target Gene
MDM2
Gene ID
4193
Label or Dye
Unconjugated
Purification
Affinity Purified
Research Category
Apoptosis
Cell Cycle & Proliferation
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

337100
d39d292a6007e692f1e364912b99a859_CmgtBuyProduct

Pierce™ MDM2 Antibody (4H26L4), Abfinity™ Rabbit Monoclonal (Novex™)

This antibody is predicted to react with mouse based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
4H26L4
Antibody Fragment
Whole Antibody
Gene ID
4193
Gene Symbol
MDM2
Accession Number
Q00987
Label or Dye
Unconjugated
Purification
Purified
Form
Liquid
Neutralizing Antibody
No
Research Category
Apoptosis
Cell Cycle & Proliferation
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700555
c04d3c0492b884f704463aa9c63d4313_CmgtBuyProduct

Novex™ Phospho-MDM2 pSer166 Antibody

MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inacti ...

Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A14014
a46e2aa3fdf3d383c2b7fe342962a484_CmgtBuyProduct

Pierce™ MDM2 Antibody (Thermo Scientific™)

PA5-27237 targets MDM2 in IF and IHC (P) applications and shows reactivity with human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA527237
22bd01773c75422084b7fa1d88868945_CmgtBuyProduct

Pierce™ MDM2 Antibody (IF2) (Thermo Scientific™)

This antibody recognizes the ~90 kDa (apparent MW) MDM2 protein. Also recognizes isoforms at ~57 and ~74/76 kDa. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA1113
dd4ef5a06a2a02959dbc6bec3503f00d_CmgtBuyProduct

MDM2 Mouse Monoclonal Antibody (clone IF2), Concentrate

This monoclonal antibody reacts specifically with human MDM2 protein. Overexpression of MDM2 protein has been detected in a variety of human tumors, and appears to result from gene amplification, increased transcript level, and enhanced translation. Reactivity with mouse MDM2 pro ...

Specifications

Reactivity
Human
Validated Application
Immunohistochemistry (FFPE)
Host
Mouse
SubClass (Isotype)
IgG2b, kappa
Clonality
Monoclonal
Target Gene
MDM2
Gene ID
4193
Label or Dye
Unconjugated
Dilution
Concentrate Antibody
Shipping Condition
Wet Ice
Regulatory Statement
For In Vitro Diagnostic Use.

Related Applications

182403
f3f50cff3c1fb8a825934e9d58c8dbab_CmgtBuyProduct

Novex™ Phospho-MDM2 pSer166 Antibody (Novex™)

MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inacti ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
MDM2 [pS166]
Gene ID
4193, 17246
Label or Dye
Unconjugated
Target Modification State
Phospho
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441400G
94b47c813707d51afd3602a3f33c0168_CmgtBuyProduct

Pierce™ Phospho-MDM2 pSer166 Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517744
274d9c9c21e71ab440c8a2f727d4383d_CmgtBuyProduct

Pierce™ Phospho-MDM2 pSer395 Antibody (Thermo Scientific™)

MDM2 is a target of the transcription factor tumor protein p53. This protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inactivation ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA513008
2a09e628f75b2a67e6bcd054199dd3ab_CmgtBuyProduct

Pierce™ Mdm2 Antibody (Thermo Scientific™)

MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inacti ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA511353
c8e59747d8cb6c5eb1c48a993466e13d_CmgtBuyProduct

Pierce™ Phospho-MDM2 pThr218 Antibody (Thermo Scientific™)

MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inacti ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512919
a0b13aab13fcacd92fee621ea6adc3b0_CmgtBuyProduct

Pierce™ Phospho-MDM2 pSer166 Antibody (Thermo Scientific™)

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as an ubiquitin ligase E3 towar ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535490
1a7cdf90c936fa9f8fedabb12e72870d_CmgtBuyProduct

Pierce™ MDM2 Antibody (Thermo Scientific™)

A suggested positive control for this product is K562 cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
099b3991d094cd30e73e6f6c2b5a5ff6_CmgtBuyProduct

Pierce™ MDM2 Antibody (SMP14) (Thermo Scientific™)

MA1-23318 detects MDM2 in Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
90b72f8a88b58bb27a8062791fee08b0_CmgtBuyProduct

Pierce™ Phospho-MDM2 pSer185 Antibody (Thermo Scientific™)

PA1-31438 detects MDM2 from human and mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA131438
07cf173d421849b766419e921a0707f4_CmgtBuyProduct