Genomics and proteomics search results

Novex™ MEKK3 Antibody (D36G5)

This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appea ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D36G5
Antibody Fragment
Whole Antibody
Gene ID
4215
Gene Symbol
MAP3K3
Accession Number
Q99759
Gene Aliases
MAP3K3, MAPKKK3, MEKK3
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Ser/Thr Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
MAPK Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16697
6d04edf8acc545bd7519ae6bd90d6877_CmgtBuyProduct

MAP3K3 (MEKK3) Recombinant Human Protein

MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks. ...

Specifications

Gene ID
114294, 4215
Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 3
Gene Aliases
MAP3K3 (MEKK3)
Kinase Group
Ser⁄Thr Kinases: STE Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002392
Molecular Weight
99.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Tag Position
N-Terminal
Expression
Baculovirus
Kinase Family
STE11 Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3876
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LanthaScreen® Tb-pMAP2K1 (pSer217/221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate ...

Specifications

Format
384-well plate
Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Tb (Terbium)
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4813
e855eb49c706e7e710d29bba4250c25f_CmgtBuyProduct

Fluorescein-MAP2K1

Inactive MAP2K1 (MEK1) has been labeled with fluorescein, and is a substrate for MAPK family members. ...

Specifications

Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Substrate
MAP2K1
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
50000 Da
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4812
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Pierce™ MEKK3 / MAP3K3 Antibody (Thermo Scientific™)

PA5-29322 targets MEKK3 in IHC (P) and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529322
8fbc99fd1d37f7b192ff39c100d41acb_CmgtBuyProduct

Pierce™ PSME3 Antibody (20H9L19), Abfinity™ Rabbit Monoclonal (Novex™)

This antibody is predicted to react with canine, chicken, equine, orangutan, Xenopus and zebrafish based on sequence homology. ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Flow Cytometry
Western Blot
Immunohistochemistry
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
20H9L19
Antibody Fragment
Whole Antibody
Target Gene
PA28-gamma
Gene ID
10197
Accession Number
P61289
Label or Dye
Unconjugated
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
For use with (Equipment)
Fluorescence Microscope
Confocal Microscope
Flow Cytometer
Volume (Metric)
200 µl
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700180
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Novex™ Phospho-SGK1 pSer422 Antibody (Novex™)

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
SGK1 [pS422]
Gene ID
6446
Label or Dye
Unconjugated
Target Modification State
Phospho
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441264G
eb258934a152d077cff9949a996cf0cd_CmgtBuyProduct

Novex™ Phospho-SGK1 pThr256 Antibody (Novex™)

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
SGK1 [pT256]
Gene ID
6446
Label or Dye
Unconjugated
Target Modification State
Phospho
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441260G
d81e1681bde1598478038f2a5585336d_CmgtBuyProduct

Pierce™ TRAF7 Antibody (Thermo Scientific™)

Suggested positive control: antigen standard for TRAF7 (transient overexpression lysate). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA141285
d02872fbcb02fb692c8c97199b195936_CmgtBuyProduct

Pierce™ MEKK3 / MAP3K3 Antibody (Thermo Scientific™)

This antibody detects endogenous protein at a molecular weight of 71 kDa. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
5126cfbb0969a845a76a17b511f01d22_CmgtBuyProduct

Novex™ Phospho-MEK5 pSer311 + pThr315 Antibody (Novex™)

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical pro ...

Specifications

Reactivity
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG1
Clonality
Polyclonal
Clone ID
pAB
Antibody Fragment
Whole Antibody
Target Gene
MEK5 [pSpT311/315]
Gene ID
29568
Gene Symbol
MAP2K5
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Form
Frozen
Protein Family
Kinases & Inhibitors
Volume (Metric)
100 µl
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

480024
3fd624e5679be9eca4599f80cf50ba2e_CmgtBuyProduct

Pierce™ MEK5 / MAP2K5 Antibody (Thermo Scientific™)

PA5-29236 targets MEK5 in IHC (P) and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529236
9df3f74e824bbbf174237efa8fac7905_CmgtBuyProduct

Pierce™ MKK5 / MAP2K5 Antibody (Thermo Scientific™)

MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515083
a1e32b0b6c7bd08adb20609e5dae3cd3_CmgtBuyProduct

Pierce™ Phospho-SGK pSer422 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535427
5b44b1bee3d2e0ebb16a4b6a395aae1e_CmgtBuyProduct

Pierce™ Phospho-SGK1 pSer78 Antibody (Thermo Scientific™)

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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