Genomics and proteomics search results

NTRK2 (TRKB) Recombinant Human Protein

NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF). Together, NTRK2 and BDNF regulate both short-term synap ...

Specifications

Gene ID
4915
Species
Human
Target Gene
neurotrophic tyrosine kinase, receptor, type 2
Gene Aliases
NTRK2 (TRKB)
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006171
Molecular Weight
40.9 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Antibody
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 526-838
Expression
Baculovirus
Kinase Family
Neurotrophic Receptor (NTRK) Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3616
838206d8737f9de7e1d241b96841d218_CmgtBuyProduct

CellSensor® TrkB-NFAT-bla CHO-K1 Cell Line

Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death. Neurotrophin signaling also mediates higher-ord ...

Specifications

System
CellSensor™
Cell Line
CHO-K1
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1491
a0357f68740aeb6970e54cca66a7dee8_CmgtBuyProduct

Pierce™ TRKB Antibody (Thermo Scientific™)

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Horse, Rabbit (100%) Bovine (92%). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA534026
1f7021fdc8704ceab4399c074bb483b2_CmgtBuyProduct

Novex™ TrkA pTyr496 + TrkB pTyr515 Antibody (C35G9)

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and ma ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
C35G9
Antibody Fragment
Whole Antibody
Target Gene
TRKA
Gene ID
4914, 4915
Gene Symbol
NTRK1, NTRK2
Accession Number
P04629;Q16620
Gene Aliases
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, TRKB, trk-B, GP145-TrkB
Label or Dye
Unlabeled
Target Modification State
Phospho
Form
Liquid
Protein Family
Tyrosine Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Neurobiology
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16663
f68e5dbc57e1fdbf63adf44368d6fb2c_CmgtBuyProduct

Pierce™ Phospho-TrkA pTyr490+TrkB pTyr516 Antibody (H.652.3) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514926
5296d44dcd5b8e8a895493c3eb318708_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00128G
a8f485012b8322208b1f7a6c582530f8_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00127W
e2437894837429c2e355e41c578d2760_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00117W
f89d013cf0119d5800915f1c1440b2f5_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00125W
9444963082f1a873cb1a3ce2bf5752fb_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00118G
5969f62b94877b8411717a5e09e1d721_CmgtBuyProduct

Pierce™ TrkB Antibody (Thermo Scientific™)

Glycerol (1:1) may be added for additional stability. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OST00126G
c5471dc98fde4f3755a919efbf410c3b_CmgtBuyProduct

Pierce™ Phospho-TrkA pTyr674 / 675+TrkB pTyr706 / 707 Antibody (C.795.3) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514927
020bd3b2e72ea1f8aea7fc22d847d4e9_CmgtBuyProduct

Pierce™ TrkB Antibody (J.977.7) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514903
25fba7b9e867174be42de5f186e1621a_CmgtBuyProduct

Novex™ TrkB Antibody (80E3)

Neurotrophins activate tyrosine kinase receptors of the trk family (trkA, trkB and trkC) and they all share a common low affinity receptor (p75NTR or p75). Although p75NTR does not appear to directly transduce NGF signals, this receptor appears to increase the responsiveness of t ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
80E3
Antibody Fragment
Whole Antibody
Target Gene
TrkB
Gene ID
4915
Gene Symbol
NTRK2
Accession Number
Q16620
Gene Aliases
TRKB, trk-B, GP145-TrkB
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Tyrosine Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Neurobiology
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16661
0c909a27f09cfec7610b9adb0c622579_CmgtBuyProduct

Pierce™ Phospho-TrkB pTyr705 Antibody (Thermo Scientific™)

Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurot ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535546
f9ea94437c77dd2ef9a736021f736b20_CmgtBuyProduct