Genomics and proteomics search results

Pierce™ PIK3CA Antibody (4F3) (Thermo Scientific™)

MA5-17149 targets PIK3CA in FACS, ICC, IF and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA517149
54c7ca2a6805312da957443f08c4899a_CmgtBuyProduct

Pierce™ PIK3CA / P110alpha Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA518610
13c44bd89514a76c4fba47dd2f66ee41_CmgtBuyProduct

PIK3CA/PIK3R1 (p110 alpha/p85 alpha) Recombinant Human Protein

PIK3CA (p110 alpha) is known to be involved in the PI 3-kinase⁄AKT signaling pathway, which plays an important role in regulating cell growth and apoptosis. PIK3CA is coexpressed and copurified with the regulatory subunit PI3KR1. ...

Specifications

Gene ID
5290
Species
Human
Expression
Baculovirus
Target Gene
phosphoinositide-3-kinase, catalytic, alpha polypeptide
Gene Aliases
PIK3CA/PIK3R1 (p110 alpha/p85 alpha), PI3 Kinase alpha
Kinase Group
Lipid Kinases
Tag Position
His (N-Terminal)⁄None
Protein Family
Kinases & Inhibitors
Protein Subtype
Lipid Kinases
Accession Number
NP_003209.2 ⁄ NP_852664.1
Molecular Weight
128.4⁄83.6 kDa
Research Category
Signal Transduction
System Compatibility
Adapta™
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Kinase Family
PI3 Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4788
d8caed791a348daa97cccc4fcc18dbde_CmgtBuyProduct

WORTMANNIN (Novex™)

Wortmannin, a fungal metabolite, is a potent and selective inhibitor of phosphatidylinositol 3-kinase. ...

Specifications

Form
Solid
Gene ID
5290, 5291, 5293, 5294
Sterility
Nonsterile
Purification
TLC
Inhibitor Type
Kinase Inhibitor
Kinase Inhibitor (PI 3-Kinase Inhibitor)
Molecular Weight
428.4 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PI3-Kinase
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1301
69737c937ea91d67a2ace5599794a2df_CmgtBuyProduct

CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line

The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression (DBE-bla), along with a tetracycline repressor and tetracycline (or the tetracycline analog ...

Specifications

System
CellSensor™
Cell Line
HeLa
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1468
9d8103264213ce2b747f50b22caa6c24_CmgtBuyProduct

Pierce™ PI3 kinase p110 alpha Antibody (Thermo Scientific™)

PA5-27192 targets PI3 kinase p110 alpha in IHC (P) and WB applications and shows reactivity with Human and mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA527192
7b5ce88f7512f90bac5d511584b42e6c_CmgtBuyProduct

Pierce™ PI3 Kinase p110-alpha Antibody (H.843.0) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514870
efd32640eed0bea1c1c69df84c717ab3_CmgtBuyProduct

PIP2:PS Lipid Kinase Substrate

Specifically optimized for use with the Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), this substrate consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphoserine (PS). ...

Specifications

Gene ID
5290, 5294
Substrate
Phosphoinositol-4,5-bisphosphate (PIP2) lipid vesicles with phosphoserine (PS)
Target Enzyme
Lipid Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
PIK3CA, PIK3CG, PIK3CB, PIK3CD
Substrate Properties
Lipid-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5100
0cf73d7f441a0339d80cd0a8bd11807b_CmgtBuyProduct

AcroMetrix® MultiMixB FFPE Control (Applied Biosystems™)

AcroMetrix® MultiMix FFPE controls are process controls for assessing the performance of methods for the isolation, purification, and detection of somatic genetic variants in research oncology testing. The control consists of 5 single-use samples of a synthetic tissue that has be ...

Specifications

Target Gene
FBXW7
RET
PDGFRA
EGFR
KRAS
FLT3
KDR
TP53
APC
FGFR3
PIK3CA
Control Type
Molecular Control
Positive Control
Assay Type
Nucleic Acid Testing (Qualitative)
Nucleic Acid Testing (Quantitative)
Calibration
Test Category
Oncology
Sample Treatment
FFPE (Formalin-Fixed, Paraffin-Embedded)
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
For use with (Equipment)
AmpliSeq Cancer HotSpot Panel V2
957185
361b399d0788e7b19a05b911af5cc853_CmgtBuyProduct

AcroMetrix® MultiMixA FFPE Control (Applied Biosystems™)

AcroMetrix® MultiMix FFPE controls are process controls for assessing the performance of methods for the isolation, purification, and detection of somatic genetic variants in research oncology testing. The control consists of 5 single-use samples of a synthetic tissue that has be ...

Specifications

Target Gene
EGFR
PDGFRA
FGFR3
PIK3CA
STK11
CSF1R
GNA11
RET
FLT3
FBXW7
TP53
HNF1A
HRAS
VHL
Control Type
Molecular Control
Positive Control
Assay Type
Nucleic Acid Testing (Qualitative)
Nucleic Acid Testing (Quantitative)
Calibration
Test Category
Oncology
Sample Treatment
FFPE (Formalin-Fixed, Paraffin-Embedded)
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
For use with (Equipment)
AmpliSeq Cancer HotSpot Panel V2
957184
54376be02cdda8deae06c0ea47d52ef5_CmgtBuyProduct

AcroMetrix® MultiMixF FFPE Control (Applied Biosystems™)

AcroMetrix® MultiMix FFPE controls are process controls for assessing the performance of methods for the isolation, purification, and detection of somatic genetic variants in research oncology testing. The control consists of 5 single-use samples of a synthetic tissue that has be ...

Specifications

Target Gene
KIT
EGFR
PDGFRA
SMARCB1
CSF1R
KRAS
KDR
FLT3
MET
SMO
TP53
FGFR1
HRAS
FGFR3
PIK3CA
NOTCH1
Control Type
Molecular Control
Positive Control
Assay Type
Nucleic Acid Testing (Qualitative)
Nucleic Acid Testing (Quantitative)
Calibration
Test Category
Oncology
Sample Treatment
FFPE (Formalin-Fixed, Paraffin-Embedded)
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
For use with (Equipment)
AmpliSeq Cancer HotSpot Panel V2
957189
7c747d3b1e84e245aff14c34f414b9ad_CmgtBuyProduct

AcroMetrix® MultiMixH FFPE Control (Applied Biosystems™)

AcroMetrix® MultiMix FFPE controls are process controls for assessing the performance of methods for the isolation, purification, and detection of somatic genetic variants in research oncology testing. The control consists of 5 single-use samples of a synthetic tissue that has be ...

Specifications

Target Gene
FLT3
KRAS
PDGFRA
CSF1R
EGFR
RET
STK11
IDH1
TP53
APC
HRAS
FGFR3
PIK3CA
Control Type
Molecular Control
Positive Control
Assay Type
Nucleic Acid Testing (Qualitative)
Nucleic Acid Testing (Quantitative)
Calibration
Test Category
Oncology
Sample Treatment
FFPE (Formalin-Fixed, Paraffin-Embedded)
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
For use with (Equipment)
AmpliSeq Cancer HotSpot Panel V2
957191
01dd6960ee22ff9f2312999a0dfb5d52_CmgtBuyProduct

AcroMetrix® Oncology Hotspot Control

The AcroMetrix® Oncology Hotspot Control is a highly multiplexed quality control used to assess the performance of next-generation sequencing (NGS) assays that detect somatic mutations. ...

Specifications

Target Gene
CDH1
PTEN
FBXW7
IDH2
MPL
EZH2
MET
KIT
JAK3
JAK2
RB1
RET
ABL1
CTNNB1
MSH6
FLT3
FGFR2
BRAF
EGFR
SRC
MAP2K1
ERBB2
MLH1
ALK
KRAS
VHL
GNAQ
FOXL2
CDKN2A
NRAS
ATM
NPM1
GNA11
FGFR3
GNAS
IDH1
SMO
SMAD4
TP53
FGFR1
ERBB4
APC
HNF1A
HRAS
PIK3CA
NOTCH1
KDR
STK11
PDGFRA
SMARCB1
CSF1R
PTPN11
AKT1
Control Type
Molecular Control
Positive Control
Test Category
Oncology
Regulatory Statement
For In Vitro Diagnostic Use.
969056
42e3b689ba0e0d7c97cb0e5fd9948c44_CmgtBuyProduct

Pierce™ PI3KCA Antibody (Thermo Scientific™)

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogen ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515246
4def5685ca7e19d09ce8e801dc6e4475_CmgtBuyProduct