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2D Labtainer™ BioProcess Container (BPC), ASI™ 26/77 film, 3 ports, capsule filter, MPC insert, injection port (Thermo Scientific™)

The 10 L Thermo Scientific™ BioProcess Container (BPC) 2D System is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, a single-web, multi-layer 12.5 mL film. This BPC includes 3 ports (1 membrane capsule filter, MPC insert, pinch clamps, and an injection site).

Features
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• Constructed in an ISO 7 clean room under cGMP conditions

Applications
• Harvesting from, feeding into, and collecting samples from bioreactors and fermenters
• Preparing and storing buffer, culture media, and process liquids
• Collecting chromatography feeds and fractions
• Harvesting, storing, and transporting bulk drug product and drug precursors

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors
• Filters (used for bioburden reduction )—sterilization grade filters, vent filters
• Tubing—thermoplastic elastomers, platinum-cured silicone
• Sample ports—septum-style ports, needle-free ports
• Clamps—sliders, pinch clamps, crimp bands

BPC port specifications:
• Line 1: 0.2 μm PES membrane capsule filter + pinch clamp. Tubing: C-Flex 374, length: 30.5 cm (12 in.), ID x OD: 9.5 x 15.9 mm (0.38 x 0.63 in.)
• Line 2: MPC insert + cap, pinch clamp. Tubing: C-Flex 374, length: 91.4 cm (36 in.), ID x OD: 9.5 x 15.9 mm (0.38 x 0.63 in.)
• Line 3: Injection site

DHX™ Heat Exchanger BioProcess Container (BPC), ASI™ 26/77 film, ReadyMate connections, four 6-L BPCs (Thermo Scientific™)

The Thermo Scientific™ DHX™ Heat Exchanger Single-Use BioProcess Container (BPC) is a 2D system consisting of four 6 L BPCs, without drain. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and ReadyMate DAC end connections. The DHX Heat Exchanger and DHX BPC each features a serpentine pattern, creating a sterile fluid path for the process fluid. The BPC fits tightly between the stainless steel DHX Heat Exchanger plate system, and after loading, no further operator interaction is required. The customer has the option of utilizing up to 4 BPCs in the DHX unit.

Features
• Eliminates post-use cleaning steps required with reusable containers, helping to reduce cross-contamination risks
• Provides sterile processing environment without the cost and time of clean-in-place or steam-in-place sterilization (CIP/SIP)
• Minimizes bioburden by using the DHX Heat Exchanger unit and DHX BPCs to address weak points in a CIP system or sanitation process (typically required for stainless steel equipment)
• Reduces maintenance and life cycle cost due to its unique design
• Increases volume capacity via parallel connection between DHX units

Applications
• cGMP commercial and clinical biotherapeutics, vaccines, and other biologic processes
• Upstream applications, including media hold, harvest cooling, and harvest hold
• Downstream applications, including harvest hold, buffers, protein purification, and bulk drug substance

2D Labtainer™ BioProcess Container (BPC), ASI™ 26/77 film, 2 ports, capsule filter and MPC insert (Thermo Scientific™)

The 50 L Thermo Scientific™ BioProcess Container (BPC) 2D System is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, a single-web, multi-layer 12.5 mL film. This BPC includes 2 ports (1 membrane capsule filter and 1 MPC insert with pinch clamps).

Features
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• Constructed in an ISO 7 clean room under cGMP conditions

Applications
• Harvesting from, feeding into, and collecting samples from bioreactors and fermenters
• Preparing and storing buffer, culture media, and process liquids
• Collecting chromatography feeds and fractions
• Harvesting, storing, and transporting bulk drug product and drug precursors

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors
• Filters (used for bioburden reduction )—sterilization grade filters, vent filters
• Tubing—thermoplastic elastomers, platinum-cured silicone
• Sample ports—septum-style ports, needle-free ports
• Clamps—sliders, pinch clamps, crimp bands

BPC port specifications:
• Line 1: 0.2 μm PES membrane capsule filter + pinch clamp. Tubing: C-Flex 374, length: 91.4 cm (36 in.), ID x OD: 9.5 x 15.9 mm (0.38 x 0.63 in.)
• Line 2: MPC insert + cap, pinch clamp. Tubing: C-Flex 374, length: 91.4 cm (36 in.), ID x OD: 9.5 x 15.9 mm (0.38 x 0.63 in.)

imPULSE™ Single-Use Mixer BioProcess Container (BPC), ASI™ 26/77 film (Thermo Scientific™)

The 500 L Thermo Scientific™ imPULSE™ Single-Use Mixer (S.U.M.) BioProcess Container (BPC) is a 3D system composed of Thermo Scientific™ ASI™ 26/77 Polyethlyene Film that includes 5 ports (3 top ports, 2 bottom ports).

BPC port specifications:
• Line 1: MPX body + cap
   Tubing: Silicone, length: 30.48 cm (12 in.)
   ID x OD: 1.27 x 1.91 cm (0.5 x 0.75 in.)
• Line 2: MPX body + cap
   Tubing: Silicone, length: 30.48 cm (12 in.)
   ID x OD: 1.27 x 1.91 cm (0.5 x 0.75 in.)
• Line 3: MPX body + cap
   Tubing: Silicone, length: 30.48 cm (12 in.)
   ID x OD: 1.27 x 1.91 cm (0.5 x 0.75 in.)
• Line 4: MPX body + cap
   Tubing: Silicone, length: 30.48 cm (12 in.)
   ID x OD: 1.27 x 1.91 cm (0.5 x 0.75 in.)
• Line 5: Tri-clover powder port with gasket (7.62 cm (3 in.)), end cap, and clamp

In addition, standard transfer assemblies to connect the imPULSE S.U.M. BPC for recirculation, inflation, and vent control are available. These assemblies are modular and can be customized to best suit your bioproduction processes.

Features
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• Designed to fit the full range of support containers, both square and cylindrical (50 L–5,000 L)

Applications
• Powder media hydration
• Liquid media concentration dilution
• Serves as a harvest hold tank
• Viral inactivation
• Allows harvesting from, and feeding into, bioreactors and fermentors
• Downstream intermediate pooling
• Final product hold and additive suspension

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 20,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors
• Filters (for bioburden reduction)—sterilization grade filters, vent filters
• Tubing—thermoplastic elastomers, platinum-cured silicone
• Sample ports—septum-style ports, needle-free ports
• Clamps—sliders, pinch clamps, crimp bands

2D Labtainer™ BioProcess Container (BPC), ASI™ 26/77 film, 3 ports, ReadyMate connectors and injection site (Thermo Scientific™)

The 5 L Thermo Scientific™ BioProcess Container (BPC) 2D System is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, a single-web, multi-layer 12.5 mL film. This BPC includes 3 ports (2 ReadyMate pinch clamps, 1 injection site).

Features
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• Constructed in an ISO 7 clean room under cGMP conditions

Applications
• Harvesting from, feeding into, and collecting samples from bioreactors and fermenters
• Preparing and storing buffer, culture media, and process liquids
• Collecting chromatography feeds and fractions
• Harvesting, storing, and transporting bulk drug product and drug precursors

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors
• Filters (used for bioburden reduction )—sterilization grade filters, vent filters
• Tubing—thermoplastic elastomers, platinum-cured silicone
• Sample ports—septum-style ports, needle-free ports
• Clamps—sliders, pinch clamps, crimp bands

BPC port specifications:
• Line 1: ReadyMate connection and pinch clamp. Tubing: C-Flex 374, length: 30 cm (12 in.), ID x OD: 9.5 x 16 mm (0.38 x 0.63 in.)
• Line 2: ReadyMate connection and pinch clamp. Tubing: C-Flex 374, length: 30 cm (12 in.), ID x OD: 9.5 x 16 mm (0.38 x 0.63 in.)
• Line 3: Injection port

Accent™ Plastic Outer Container 3D BioProcess Container (BPC), ASI™ 26/77 film, 3 ports, MPX inserts and Kleenpak connector (Thermo Scientific™)

The 1,000 L Thermo Scientific™ Single-Use 3D BioProcess Container (BPC) is a 3D BPC designed for use within the Thermo Scientific™ Accent™ Plastic Outer Container. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and three ports (2 MPX insert + cap, 1 Kleenpak body connector with ½-inch barb). The plastic outer container provides support for the BPC, eliminating the need for complicated on-site sterilizing and cleaning procedures. Large volumes of cell culture media, buffers, or other liquids remain clean and ready to use directly from the outer container. Together, the Accent outer container and BPC form a system for collecting, storing, and dispensing fluids used in bioprocessing operations. Not intended for shipping applications.

BPC port specifications:
• Line 1: MPX insert with cap and pinch clamp
   Tubing: Silicone, length: 50.8 cm (20 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 2: Kleenpak body connector with 12.7 cm (0.5 in) barb and pinch clamp
   Tubing: Silicone, length: 91.4 cm (36 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 3: MPX insert with cap and pinch clamp
   Tubing: Silicone, length: 50.8 cm (20 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)

Applications
• Storing and transporting sterile media and buffers within facility
• Feeding sterile media into bioreactors and buffers into purification systems
• Receiving and storing harvest from bioreactors

2D Labtainer™ BioProcess Container (BPC), ASI™ 28 film, 1 port, Luer Lock connector (Thermo Scientific™)

The 10 L Thermo Scientific™ Labtainer™ BioProcess Container (BPC) 2D system is composed of Thermo Scientific™ ASI™ 28 film, a 4-layer, 12.5 mL, animal origin–free ethyl vinyl acetate film and includes 1 port (1 luer body + cap).

Features of the system include:
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• All Labtainers constructed in an ISO 7 cleanroom environment under cGMP conditions

Applications include:
• Harvesting from, feeding into, and collecting samples from bioreactors and fermenters
• Preparing and storing buffer, culture media, and process liquid
• Collecting chromatography feed and fraction
• Harvesting, storing, and transporting bulk drug product and drug precursors

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, and cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, and steam-to and steam-through connectors
• Filters (used for bioburden reduction)—sterilization grade filters and vent filters
• Tubing—thermoplastic elastomers and platinum-cured silicone
• Sample ports—septum-style and needle-free ports
• Clamps—sliders, pinch, and crimp bands

imPULSE™ Single-Use Mixer Recirculation Transfer Assembly (Thermo Scientific™)

The Thermo Scientific™ Recirculation Transfer Assembly, 1.9 cm (.75 in.), consists of silicone tubing with MPU inserts with caps and a sanitary barb with a gasket, end cap, push/pull clip, and swab-able sample port. This transfer assembly is compatible with the Thermo Scientific™ imPULSE™ Single-Use BioProcess Container (BPC), ranging from 1000 L to 3000 L.

Features
• Minimizes bioburden due to construction under sterile cGMP conditions.

Tubing specifications:
• Tubing: Silicone with size 90 pharmed BPT pump tubing, ID x OD: 1.91 x 2.86 cm (0.75 x 1.125 in.)
• T1-T2: MPU insert + cap
• T3: 3.8 cm (1.5 in.) sanitary x 1.91 cm (0.75 in.) barb with gasket, end cap, push/pull clip
• T4: Sample port

Accent™ Plastic Outer Container 3D BioProcess Container (BPC), ASI™ 26/77 film, 3 ports, MPX inserts and ReadyMate connector (Thermo Scientific™)

The 1,000 L Thermo Scientific™ Single-Use 3D BioProcess Container (BPC) is a 3D BPC designed for use within the Thermo Scientific™ Accent™ Plastic Outer Container. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and three ports (2 MPX insert + cap, 1 ReadyMate DAC with ½-inch barb). The plastic outer container provides support for the BPC, eliminating the need for complicated on-site sterilizing and cleaning procedures. Large volumes of cell culture media, buffers, or other liquids remain clean and ready to use directly from the outer container. Together, the Accent outer container and BPC form a system for collecting, storing, and dispensing fluids used in bioprocessing operations. Not intended for shipping applications.

BPC port specifications:
• Line 1: MPX insert + cap, pinch clamp
   Tubing: Silicone, length: 50.8 cm (20 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 2: ReadyMate connector with 12.7 cm (0.5 in) barb and pinch clamp
   Tubing: Silicone, length: 91.4 cm (36 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 3: MPX insert with cap and pinch clamp
   Tubing: Silicone, length: 50.8 cm (20 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)

Applications
• Storing and transporting sterile media and buffers within facility
• Feeding sterile media into bioreactors and buffers into purification systems
• Receiving and storing harvest from bioreactors

Accent™ Plastic Outer Container 3D BioProcess Container (BPC), ASI™ 26/77 film, 4 ports, MPC insert, Luer Lock body, Ladish Tri-Clovers (Thermo Scientific™)

The 1,000 L Thermo Scientific™ Single-Use 3D BioProcess Container (BPC) is a 3D BPC designed for use within the Thermo Scientific™ Accent™ Plastic Outer Container. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and four ports (1 MPX insert + cap, 1 luer lock body connection + valve + cap, 2, 1.5-inch Ladish tri-clover). The plastic outer container provides support for the BPC, eliminating the need for complicated on-site sterilizing and cleaning procedures. Large volumes of cell culture media, buffers, or other liquids remain clean and ready to use directly from the outer container. Together, the Accent outer container and BPC form a system for collecting, storing, and dispensing fluids used in bioprocessing operations. Not intended for shipping applications.

BPC port specifications:
• Line 1: MPX insert + cap, pinch clamp
   Tubing: C-Flex (clear), length: 152.4 cm (60 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 2: Luer lock body connection + valve + cap, pinch clamp
   Tubing: C-Flex (clear), length: 101.6 cm (40 in.)
   ID x OD: 3.16 x 6.4 mm (0.125 x 0.25 in.)
• Line 3: Ladish tri-clover, pinch clamp
   Tubing: C-Flex (clear), length: 152.4 cm (60 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)
• Line 4: Ladish tri-clover, pinch clamp
   Tubing: C-Flex (clear), length: 152.4 cm (60 in.)
   ID x OD: 12.7 x 19.1 mm (0.5 x 0.75 in.)

Applications
• Storing and transporting media and buffers within facility
• Feeding sterile media into bioreactors and buffers into purification systems
• Receiving and storing harvest from bioreactors

Labtainer™ BioProcess Container (BPC), 50Lwith 3 Ports, MPC Insert, MPC Body, and Luer Lock, 2D BPC (Thermo Scientific™)

The 50 L Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single web, multi-layer plastic film and includes 3 top ports (MPC insert, MPC body, and luer lock body connection).

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

Labtainer™ BioProcess Container (BPC), 20L with 3 Ports, Luer Lock, 2D BPC (Thermo Scientific™)

The 20 L Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single web, multi-layer plastic film and includes 3 top ports (2 luer lock bodies, 1 luer lock insert).

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

2D Labtainer™ BioProcess Container (BPC), ASI™ 28 film, 3 ports, Luer Lock connectors, injection site (Thermo Scientific™)

The 1 L Thermo Scientific™ Labtainer™ BioProcess Container (BPC) 2D system is composed of Thermo Scientific™ ASI™ 28 film, a 4-layer, 12.5 mL, animal origin–free ethyl vinyl acetate film and includes 3 ports (2 1/8-inch ID x ¼-inch OD clear C-Flex 374 (12 in.) + cap and side clamp, 1 injection site).

Features of the system include:
• Helps to eliminate post-use cleaning steps required with reusable containers, and to reduce cross-contamination risks
• All Labtainers constructed in an ISO 7 cleanroom environment under cGMP conditions

Applications include:
• Harvesting from, feeding into, and collecting samples from bioreactors and fermenters
• Preparing and storing buffer, culture media, and process liquid
• Collecting chromatography feed and fraction
• Harvesting, storing, and transporting bulk drug product and drug precursors

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, and cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, and steam-to and steam-through connectors
• Filters (used for bioburden reduction)—sterilization grade filters and vent filters
• Tubing—thermoplastic elastomers and platinum-cured silicone
• Sample ports—septum-style and needle-free ports
• Clamps—sliders, pinch, and crimp bands

imPULSE™ Single-Use Mixer Vent Line Transfer Assembly (Thermo Scientific™)

The Thermo Scientific™ Vent Transfer Assembly, 1.9 cm (.75 in.), consists of silicone tubing with MPU inserts with caps and a sanitary barb with a gasket, end cap, and push/pull clip. This transfer assembly is compatible with the Thermo Scientific™ imPULSE™ Single-Use BioProcess Containers (BPC), ranging from 1,000 L to 3,000 L.

Features
• Minimizes bioburden due to construction under sterile cGMP conditions

Tubing specifications:
• Tubing: Silicone, 22.9 x 22.9 x 182.9 cm (9 x 9 x 72 in.), ID x OD: 1.91 x 2.86 cm (0.75 x 1.125 in.)
• T1: MPU body + cap
• T2: MPU insert + cap
• T3:3.8 cm (1.5 in.) sanitary x 1.91 cm (0.75 in.) barb with gasket, end cap, push/pull clip

DHX™ Heat Exchanger BioProcess Container (BPC), ASI™ 26/77 film, ReadyMate connections, drain ports, two 6-L BPCs (Thermo Scientific™)

The Thermo Scientific™ DHX™ Heat Exchanger Single-Use BioProcess Container (BPC) is a 2D system consisting of two 6 L BPCs, with drain. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and ReadyMate DAC end connections. The DHX Heat Exchanger and DHX BPC each features a serpentine pattern, creating a sterile fluid path for the process fluid. The BPC fits tightly between the stainless steel DHX Heat Exchanger plate system, and after loading, no further operator interaction is required. The customer has the option of utilizing up to 4 BPCs in the DHX unit.

Features
• Eliminates post-use cleaning steps required with reusable containers, helping to reduce cross-contamination risks
• Provides sterile processing environment without the cost and time of clean-in-place or steam-in-place sterilization (CIP/SIP)
• Minimizes bioburden by using the DHX Heat Exchanger unit and DHX BPCs to address weak points in a CIP system or sanitation process (typically required for stainless steel equipment)
• Reduces maintenance and life cycle cost due to its unique design
• Increases volume capacity via parallel connection between DHX units

Applications
• cGMP commercial and clinical biotherapeutics, vaccines, and other biologic processes
• Upstream applications, including media hold, harvest cooling, and harvest hold
• Downstream applications, including harvest hold, buffers, protein purification, and bulk drug substance