Reductively labile PRINT particles for the delivery of doxorubicin to HeLa cells.

Citations & References

  • Authors: Petros RA, Ropp PA, DeSimone JM,
  • Journal: J Am Chem Soc (2008) 130:5008-5009
  • ID: PN68429
f8dc55f175972a64dc2b407ef35e4975_Citations

Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

Citations & References

  • Authors: Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C,
  • Journal: Cancer Res (2006) 66:11851-11858
  • ID: PN141110
86344ef2be3b01aa0a1f407aeb9e0229_Citations

Antiangiogenic activity of 2-deoxy-D-glucose.

Citations & References

  • Authors: Merchan JR, Kovács K, Railsback JW, Kurtoglu M, Jing Y, Piña Y, Gao N, Murray TG, Lehrman MA, Lampidis TJ,
  • Journal: PLoS One (2010) 5:e13699-e13699
  • ID: PN141111
4984b6d767d9741480fdb543296dd303_Citations

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK.

Citations & References

  • Authors: Okawa Y, Hideshima T, Steed P, Vallet S, Hall S, Huang K, Rice J, Barabasz A, Foley B, Ikeda H, Raje N, Kiziltepe T, Yasui H, Enatsu S, Anderson KC,
  • Journal: Blood (2009) 113:846-855
  • ID: PN141112
34a34399aa6b476a2821539da0c3435e_Citations

Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade.

Citations & References

  • Authors: Pan Q, Bao LW, Merajver SD,
  • Journal: Mol Cancer Res (2003) 1:701-706
  • ID: PN141113
d6fb10559425e05bc82f41afceb2d09d_Citations

Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway.

Citations & References

  • Authors: Qin L, Zhang M,
  • Journal: J Biol Chem (2010) 285:32360-32369
  • ID: PN141114
9d61153402fb3a46d6271693140709b0_Citations

Indirubin derivative E804 inhibits angiogenesis.

Citations & References

  • Authors: Shin EK, Kim JK,
  • Journal: BMC Cancer (2012) 12:164-164
  • ID: PN141115
0b3a392600a8e641d48008b03034529b_Citations

Systems biology in cancer research: genomics to cellomics.

Citations & References

  • Authors: Stilwell JL, Guan Y, Neve RM, Gray JW,
  • Journal: Methods Mol Biol (2007) 356:353-365
  • ID: PN141116
bb0379312e99bc6704f43131ffc6e9bf_Citations

LY2228820 dimesylate, a selective inhibitor of p38 mitogen-activated protein kinase, reduces angiogenic endothelial cord formation in vitro and in vivo.

Citations & References

  • Authors: Tate CM, Blosser W, Wyss L, Evans G, Xue Q, Pan Y, Stancato L,
  • Journal: J Biol Chem (2013) 288:6743-6753
  • ID: PN141117
3a91c47cd2dce3d04859e79249af5d57_Citations

The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.

Citations & References

  • Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY,
  • Journal: J Immunol (2007) 179:3742-3751
  • ID: PN141118
a6b6ee8e0acf10385352a42eeb42e7dd_Citations

Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR.

Citations & References

  • Authors: Tian F, Zhu CH, Zhang XW, Xie X, Xin XL, Yi YH, Lin LP, Geng MY, Ding J,
  • Journal: Mol Pharmacol (2007) 72:545-552
  • ID: PN141119
16645d817263f82490ac062d15176fb0_Citations

AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.

Citations & References

  • Authors: Wedge SR, Kendrew J, Hennequin LF, Valentine PJ, Barry ST, Brave SR, Smith NR, James NH, Dukes M, Curwen JO, Chester R, Jackson JA, Boffey SJ, Kilburn LL, Barnett S, Richmond GH, Wadsworth PF, Walker M, Bigley AL, Taylor ST, Cooper L, Beck S, Jürgensmeier JM, Ogilvie DJ,
  • Journal: Cancer Res (2005) 65:4389-4400
  • ID: PN141120
6b4d4aca7efb4da6e19045ac9f458010_Citations

Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes.

Citations & References

  • Authors: Willard MD, Lajiness ME, Wulur IH, Feng B, Swearingen ML, Uhlik MT, Kinzler KW, Velculescu VE, Sjöblom T, Markowitz SD, Powell SM, Vogelstein B, Barber TD,
  • Journal: Mol Cancer Res (2012) 10:739-749
  • ID: PN141121
9426c819ebc756106bc910348595f747_Citations

Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway.

Citations & References

  • Authors: Yang CL, Liu YY, Ma YG, Xue YX, Liu DG, Ren Y, Liu XB, Li Y, Li Z,
  • Journal: PLoS One (2012) 7:e37960-e37960
  • ID: PN141122
f9027a74e3cdb4813b94c0659d4f65c4_Citations

The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization.

Citations & References

  • Authors: Yang NY, Pasquale EB, Owen LB, Ethell IM,
  • Journal: J Biol Chem (2006) 281:32574-32586
  • ID: PN141123
427e7f3a693e0fae7c6d57931736b264_Citations