Invitrogen TRIzol

Invitrogen TRIzol products are referenced in thousands of journal publications, reflecting the trust that molecular biologists have placed in TRIzol Reagent to deliver high-quality, intact RNA from many kinds of biological materials.

TRIzol reagents are offered in several ready-to-use formats. The individual products within the TRIzol reagent family are tailored to isolate total RNA or to simultaneously isolate RNA, DNA, and protein from diverse biological sources, including samples of human, animal, plant, yeast, bacterial, and viral origin.

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RNA extraction product selection guide

Product
TRIzol Reagent
Description Isolates total RNA from tissues or cells, including lipid-rich and difficult samples
Primary Sample Type
  • Bacteria
  • Blood
  • Cells
  • Plant Samples
  • Tissue
  • Viral Samples
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product
TRIzol LS Reagent
Description Designed for use with liquid samples, such as serum or virus preparations
Primary Sample Type
  • Blood
  • Liquid Samples (e.g. Serum)
  • Viral Samples
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product
TRIzol Phasemaker Tubes
Description Creates a tight, durable seal between the aqueous and organic phase of your TRIzol mix, allowing the RNA to be easily removed and maintaining TRIzol reagent's performance
Primary Sample Type All sample types processed using any TRIzol reagent
Product Size Pre-dispensed, 2 mL tubes
  Order Now

Meet a great match for TRIzol reagents: Phasemaker Tubes

Using TRIzol reagents just got simpler, thanks to a new best friend. Invitrogen Phasemaker Tubes create a tight, durable seal between the aqueous and organic phase of your TRIzol mix. Phasemaker Tubes don’t compromise the performance of TRIzol reagents, allowing you to easily pipette off the RNA phase. It’s almost too easy.

Save money by purchasing Phasemaker Tubes together with TRIzol, TRIzol LS, or TRIzol Plus reagents, or use them with your existing TRIzol reagent.

Phasemaker Tubes

The benefits of using Phasemaker Tubes include:

  • Higher yield—increase recovery by as much as 30%
  • Ease of use—simply use with TRIzol mix, centrifuge, and then easily pipette off the aqueous phase
  • Ready-to-use convenience—comes predispensed in 2 mL tubes
  • Increased throughput—stable gel seal allows you to maximize the number of samples per run without losing phase separation
Product
TRIzol Plus RNA Purification System
Description Offers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type
  • Bacteria
  • Cells
  • Plant Samples
  • Tissue
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Microarray Analysis
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product TRIzol Max Bacterial RNA Isolation Kit
Description Offers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type Bacteria
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 preps or 200 preps
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product
TRIzol Reagent
Description Isolates total RNA from tissues or cells, including lipid-rich and difficult samples
Primary Sample Type
  • Bacteria
  • Blood
  • Cells
  • Plant Samples
  • Tissue
  • Viral Samples
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product
TRIzol LS Reagent
Description Designed for use with liquid samples, such as serum or virus preparations
Primary Sample Type
  • Blood
  • Liquid Samples (e.g. Serum)
  • Viral Samples
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product
TRIzol Phasemaker Tubes
Description Creates a tight, durable seal between the aqueous and organic phase of your TRIzol mix, allowing the RNA to be easily removed and maintaining TRIzol reagent's performance
Primary Sample Type All sample types processed using any TRIzol reagent
Product Size Pre-dispensed, 2 mL tubes
  Order Now

Meet a great match for TRIzol reagents: Phasemaker Tubes

Using TRIzol reagents just got simpler, thanks to a new best friend. Invitrogen Phasemaker Tubes create a tight, durable seal between the aqueous and organic phase of your TRIzol mix. Phasemaker Tubes don’t compromise the performance of TRIzol reagents, allowing you to easily pipette off the RNA phase. It’s almost too easy.

Save money by purchasing Phasemaker Tubes together with TRIzol, TRIzol LS, or TRIzol Plus reagents, or use them with your existing TRIzol reagent.

Phasemaker Tubes

The benefits of using Phasemaker Tubes include:

  • Higher yield—increase recovery by as much as 30%
  • Ease of use—simply use with TRIzol mix, centrifuge, and then easily pipette off the aqueous phase
  • Ready-to-use convenience—comes predispensed in 2 mL tubes
  • Increased throughput—stable gel seal allows you to maximize the number of samples per run without losing phase separation
Product
TRIzol Plus RNA Purification System
Description Offers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type
  • Bacteria
  • Cells
  • Plant Samples
  • Tissue
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 mL or 200 mL
Purification Time 1 hour
Application
  • Microarray Analysis
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now
Product TRIzol Max Bacterial RNA Isolation Kit
Description Offers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type Bacteria
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size 100 preps or 200 preps
Purification Time 1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
  Order Now

Featured videos

Phasemaker Tubes create a durable seal between the aqueous and organic phases, allowing researchers to easily pipette off the RNA phase.

Learn how to isolate ultrapure total RNA within an hour, even from difficult samples with the TRIzol Plus RNA
Purification Kit.

Technical Support - Don’t Work in Isolation - We’re here to help!

Our sample prep experts are here to help with application support, method development, or any other questions you might have for your sample prep. Please contact us directly at techsupport@thermofisher.com

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