Seminar
Jun 18, 2017 - Jun 23, 2017
Prague Congress Centre, Prague -  | 5. května 1640/65, 140 21 Praha 4 - Nusle-Praha 4, Czechia
HPLC 2017

If you were not able to attend HPLC 2017 or missed one of our presentations then please check out the resources below. You’ll be able to download our seminar and oral presentations, along with our posters.

Overview

Highlights

Thank you to everyone that visited us to discover the newest innovations in HPLC. We launched revolutionary products, delivered two lunchtime seminars, six scientific oral presentations, and twenty-four posters.

We hope to see you in Washington for HPLC 2018!

New products

Introducing the new Thermo Scientific ISQ EC single quadruple MS, giving all chromatographers easy access to mass spectrometry.

Some of the benefits of the new ISQ EC include:

  • Unmatched low mass sensitivity confirmation and chromatographic peak mass confirmation
  • Access simple, walk up workflows with The Thermo Scientific Chromeleon XPS Open Access user interface
  • Autotune feature automates instrument calibration
  • To learn more about the ISQ EC, our additional new products as well as existing liquid chromatography products visit our ISQ EC single quadruple MS page
Thermo Scientific MAbPac RP, 1.00 mm columns

Columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization with excellent resolution, long column lifetime, and low carry-over.

Learn more about the new MAbPac RP LC Columns

Lunchtime seminars

Intact Protein Analysis of Biopharmaceuticals

Monday 19th June, 12:45-13:45, Room C60
Ken Cook, EU Biopharma Support Specialist, Thermo Fisher Scientific, Hemel Hempstead, United Kingdom
Jonathan Bones, National Institute for Bioprocessing Research and Training (NIBRT), Blackrock, Ireland

Biopharmaceuticals are a rapidly growing area, but these complex biomolecules need comprehensive characterization to ensure saftey and efficacy. In this seminar, learn about the latest chromatographic workflows for biotherapeutic proteins and how you can characterize mutiple attributes with one LC-MS platform.

Biopharmaceuticals represent over $150 Billion in revenue globally each year and continues to grow. Alongside this there is the requirement for the comprehensive characterization of biopharmaceuticals during all stages of drug development and manufacture to ensure safety and efficacy. Liquid chromatography with mass spectrometry (LC-MS) allows the characterization of intact and digested biopharmaceuticals, typically antibodies, to determine glycosylation patterns, charge variants, antibody-drug conjugate ratio determination and more.

In the seminar, we will present a comprehensive overview of the latest developments in liquid chromatography separations for the characterization of bio therapeutic proteins, including new chemistries and UHPLC enhancements to provide faster, more reproducible and information-rich workflows. The use of a single UHPLC/ high resolution Orbitrap mass spectrometer platform to measure multiple critical attributes including Glycoforms, PTM’s, intact mass and sequence conformation will also be discussed and demonstrated.

Enhancements for Improved Routine Impurity Analysis

Tuesday 20th June, 12:45-13:45, Room E170
Rainer Bauder, Solutions Manager, Thermo Fisher Scientific, Chelmsford, USA

Impurities can affect the safety or quality of a product in a number of different environments with a need for efficient, sensitive and reproducible detection of such trace-level impurities. We shall highlight new technologies to enhance the analysis of impurities.

The presence of a known impurity or an unknown contaminant, even at trace levels, can have serious consequences for the safety or quality of a product or the environment, be that a pharmaceutical, food and beverage or a water/soil sample. Especially within routine and manufacturing supporting laboratories, false positives or false negatives can have significant quality impacts as well as financial consequences (i.e. loss of production batch). A range of examples will be presented, which not only provides increased quality of the assay results itself, but also employs state-of-the art trouble shooting strategies and multi-detection concepts.

This seminar will showcase our comprehensive new workflow solution for impurity analysis with a focus on pharmaceutical impurities as well as environmental testing and how quality can be assured at each stage of the workflow. We shall reveal new technology to bring mass spectrometry to chromatographers and how the Chromeleon CDS software can be used for both HPLC and IC separations and mass spectrometry, whilst ensuring data integrity and reproducible performance. Furthermore, we shall offer alternative liquid chromatography detection methodologies for difficult to detect compounds using charged aerosol detection and suppressed conductivity detection.

Oral presentations

Date & Time Session Title & Speaker
Monday, 19 June
14:00-14:30
HYP3
Separation – high-resolution MS
Theory and practice of Orbitrap mass spectrometry
Alexander Makarov, Thermo Fisher Scientific, Germany
Tuesday, 20 June
09:40-10:00
HYP5 Electrodriven separations – MS  Capillary electrophoresis – mass spectrometry for intact mass analysis of antibodies and antibody-drug-conjugates
Aran Paulus, Thermo Fisher Scientific, USA
Tuesday, 20 June
14:00-14:40
YOU 7
Ultrahigh-resolution mass spectrometry
Tutorial:
Orbitrap technology in LC/MS and GC/MS: On the road to high-resolution in every lab Alexander Makarov, Thermo Fisher Scientific, Germany
Tuesday, 20 June
15:40-16:00
FUN 8 Separation techniques for ionic compounds  New anion exchange materials based on electrostatically attached hyperbranched condensation polymers
Christopher Pohl, Thermo Fisher Scientific, USA
Tuesday, 20 June
17:20-17:40
APP 8
Glycomics and glycoproteomics
Development of a rapid and robust n-glycan analysis workflow for both LC and CE platforms Anahita Eckard, Thermo Fisher Scientific, USA
Thursday, 22 June
09:00-09:40
YOU 13
Ultrahigh-performance liquid chromatography
Tutorial: Understanding instrumental parameters that affect method transfer in UHPLC separations (some are easily overlooked) Frank Steiner, Thermo Fisher Scientific, Germany

Posters

Products

Allows any chromatographer to easily access mass spectrometry with a system that has unmatched low mass sensitivity, simple-to-use, and robust.

Resources


Columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization with excellent resolution, long column lifetime, and low carry-over.


Separate your science from the status quo. Experience uncompromised UHPLC—with no trade-offs in performance, robustness and ease of use.

Resources


Make the invisible, visible with a versatile, universal detector that adds a unique form of detection to the speed and resolution of your UPHLC system.

Resources


With the ability to use 4 μm particle size IC columns on high-pressure capable IC systems, you can finally choose between achieving even faster run times or better chromatographic resolution.

Resources


The Thermo Scientific™ nano and capillary systems are ideal for use as an integrated part of the proteomics workflow and seamlessly combine with our mass spectrometry (MS) systems

Resources


Our extensive family of products includes a variety of particle sizes and column designs to meet all separation needs, offering improved resolution, enhanced sensitivity, faster analysis and consistent performance.

Resources


Simplify your lab workflow with unified control, processing and data management for your chromatography/mass spectrometry instruments.

Resources


For all HPLC/UHPLC and LC-MS applications, each Fisher Chemical high-quality solvent undergoes rigorous quality assurance and testing measures.

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