Chromatography Data System (CDS) Software Information

Learn about its power and simplicity

A Chromatography Data System (CDS) is vital for efficient and reliable operation of any modern chromatography laboratory – it must manage the entire laboratory process from instrument control, to raw data storage and processing, right through to generating the final results.

Thermo Scientific Chromeleon CDS software provides chromatography labs with compliance-ready data management, unified instrument control and simplified analysis and data reporting for chromatography and mass spectrometry. By extending Chromeleon CDS beyond chromatography into MS, labs can now streamline chromatography and MS workflows with a single software package.

Chromeleon CDS software features


Run instruments using the same intuitive user interface, with the same methods, and provide results in the same format. Operate any instrument, any time.

White paper

White paper discussing how a fully automated workflow is in operation at Bayer Pharma AG, with a reported success of finding the target mass in about 90% of more than 9,000 reaction controls studied to date.

Case study

Learn how Regis is benefitting from a streamlined workflow through the Cobra Wizard integration tool, enhanced system suitability, and the real-time representation of the chromatography run.


Discover how Chromeleon CDS ensures you get your analysis right the first time, through an intuitive user experience software and smart, intuitive data analysis tools — reducing errors and increasing efficiency.

Chromeleon CDS software subtopics

Chromeleon CDS software overview

From fully compliant routine analyses to totally flexible research workflows or anything in between — Chromeleon CDS simplifies the entire chromatography workflow, giving better results, faster.

Compliance-ready data management

Discover how Chromeleon simplifies system administration and ensures regulatory compliance (including 21 CFR Part 11) and adherence to data integrity guidelines.

Unified Instrument Control

Chromeleon set the industry standard for multi-vendor, robust instrument control. Learn how Chromeleon continues to deliver superior instrument support through comprehensive control of Thermo Scientific IC, GC, LC, MS and over 400 third-party instruments for 16 manufacturers.

Built for mass spectrometry

Chromeleon is the first CDS that combines separation (GC/IC/LC) and Mass Spectrometry (MS) in an enterprise (client/server) environment. Learn how, by combining Chromeleon CDS with our leading GC-MS instrumentation, we provide a superior answer to the productivity challenges in the analytical laboratory.

Simplified analysis and data reporting

Discover the data processing and reporting feature that give you flexibility with simplicity—from Cobra™ peak detection and SmartPeaks™ Integration Assistant to SmartLink™ report designers and much more.

AppsLab Library of Analytical Applications

Find the best solution to your separation challenges. Search by compound, column, instrument or any other method parameter to discover the latest applications from Thermo Fisher Scientific for LC, IC, GC, GC-MS and LC-MS and easily download one-click workflows for use with Chromeleon CDS.

Chromeleon CDS Software Resources

Here’s a collection of resources to learn about the feature sets that make this software both powerful and easy to use.

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Additional Resources