Liquid Chromatography

Advanced HPLC and UHPLC solutions

Separate your science from the status quo. Thermo Scientific liquid chromatography products offer technologically advanced HPLC solutions that provide superior retention time stability, flexible lab integration with minimal maintenance for all LC applications. We offer:

  • Innovative HPLC and UHPLC systems that are robust and provide reliable chromatography with unmatched performance.
  • An extensive line of HPLC columns with a variety of particle sizes and chemistries.
  • Thermo Scientific Viper fittings that are compatible with most systems, and allow for perfect and easy tool-free LC connections that are leak-free up to 1500 bar/22,000 psi.
  • Chromeleon Chromatography Data System (CDS) software that you can streamline your chromatography and mass spectrometry workflows giving you better results, faster.

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Popular liquid chromatography products
Featured liquid chromatography categories

Discover how the innovative Vanquish UHPLC systems, our proven UltiMate 3000 Systems, and our sensitive nano-, capillary-, and microflow rate systems can help you separate your science from the status quo.

Get better resolution, sensitivity, and long-term performance with our wide selection of columns. Choose from reversed phase, HILIC, ion exchange, mixed mode, size exclusion, ligand exchange and more.

Our virtually zero-dead-volume fingertight fittings are leak-free up to 1500 bar/22,000 psi. They are easy to use allowing you to quickly connect any LC module valve or column without tools. Viper is for all HPLC and UHPLC applications.

Couple our HPLC/UHPLC systems to our mass spectrometers without losing performance and data quality. We offer unique connection kits including software and Viper fittings, for easy integration with our large mass spectrometry portfolio.

Find quality replacement parts and accessories specifically designed for your Thermo Scientific LC systems and columns.

Find derivatization reagents, standards, and reagents for amino acid and peptide applications here. Check out our ultrapure solvents for your demanding analyses.

A fully searchable analytical methods repository for LC, GC, IC applications. Download instrument and quantitation methods, as well as full eWorkflows with a few simple clicks. The fast way to get productive for novices and experts.

Whether you have a single instrument, several instruments from one or more manufacturers, or need an enterprise-wide solution, our CDS software allows for a single point of control for your chromatography mass spectrometry instruments.


Liquid chromatography components

Looking for more information on single modules? We offer each LC component separately to allow better system flexibility and accelerate your next scientific breakthrough.

Combine maximum injection precision with large sample capacity and high throughput capabilities with sample capacity extenders. Our autosamplers are optimized for ruggedness and uptime.

Retention time precision is the key to the highest confidence in your data for reliable analyte identification and quantification. Our pumps provide excellent flow accuracy and precision for nano LC, standard HPLC, and UHPLC applications.

Temperature significantly impacts retention time, selectivity, and efficiency of your column. Our column compartments allow for accurate and precise thermostatting and pre-heating so your mobile phase is the right temperature.

See more in your samples. Choose from different detectors like charged aerosol, diode array, multiple wavelength, variable wavelength, fluorescence, refractive index, and electrochemical.


Monitor your system remotely from anywhere in the world

Monitor your system remotely from anywhere in the world

  • Connect your lab to boost productivity with secure remote access to your data and instruments
  • Real-time monitoring of your instrument with automatic email notifications
  • Store data in secure accounts and share with colleagues and collaborators

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LC columns and consumables catalog

Access the latest version of our Chromatography Columns and Consumables Catalog to ensure that you're optimizing your applications! Our enhanced online version features a robust applications search tool, access to method development guides, application notebooks, and much more.

Download catalog