Vanquish UHPLC Systems

Developed without compromise

Thermo Scientific™ Vanquish™ systems were designed from the ground up to deliver a new standard in UHPLC — more results with better separations, without compromise. These easy-to-use, fully integrated and biocompatible systems feature high sample capacity for high-throughput workflows, industry-leading pumping performance, exceptionally high S/N and linearity, two-mode thermostatting, and both active and passive pre-heating preheating in a system that's driven by the gold-standard CDS software.

Popular UHPLC products
Vanquish™ Charger Module
Vanquish™ Variable Wavelength Detector F
Dionex Chromeleon 7.2 Chromatography Data System
Featured Vanquish UHPLC systems
Vanquish UHPLC System
Vanquish UHPLC System – High Performance UHPLC

Designed for extra high performance and throughput, the high-end, state-of-the-art Vanquish UHPLC system was conceived for the uniquely efficient, smaller 1.5 µm solid core particle column. The system handles samples with more accuracy, controls separations with more power and greater confidence, detects analytes with more sensitivity, and features easy maintenance with tool-free connections.

Vanquish Flex UHPLC System – Built for Biopharma

Built on our award winning Vanquish UHPLC platform, the Vanquish Flex system is designed for maximum flexibility to meet all of the necessary applications and method development for the biopharmaceutical market and any other development workflows.. This biocompatible UHPLC system includes state-of-the-art quaternary solvent blending for method development and application flexibility. The Vanquish Flex system is ideal for:

  • Aggregates
  • Fragments
  • Variants
  • Glycoforms
  • Glycan analysis
  • Peptide maps
  • Post-translational modifications (PTMs)
  • Oxidations
  • Oligonucleotides
  • Drug antibody ratios (DARs)
Vanquish Flex UHPLC System
Vanquish UHPLC system configurations and options
Featured Vanquish UHPLC system videos

Featured UHPLC webinar
Revolutionize your UHPLC Experience
Revolutionize your UHPLC experience

Frank Steiner presents the benefits and features of the Vanquish UHPLC system to revolutionize your UHPLC experience.


Are you using the right LC column?

Access the latest version of our Chromatography Columns and Consumables Catalog in PDF and online formats. The enhanced online version features a robust applications search tool, access to method development guides, application notebooks, and much more.

Download catalog ›

Meet the UHPLC system that is built for biopharma – Learn more