Fluoroquinolones are poly-aromatic compounds with fluorine atoms and carboxylic acid functionality. They are sensitive to silanol interactions with the stationary phase that can lead to compromised peak shape and reduce effective peak resolution.
Veterinary Drug Residues Testing Information
Innovative technologies to enable multi-residue detection
Antibiotics are a group of chemicals that are widely used in animal husbandry primarily for protection of animals from disease but also as growth promoters. The European Union (EU) has set maximum residue limits (MRL) for a variety of antibiotics in animal tissues, milk and eggs; suitable methods are required to be capable of detecting these residues at regulated levels. For quantitative analysis it is necessary to use instrumental techniques such as LC-MS/MS. This technique can also be used for screening, and provides much higher sensitivity and greater specificity.
Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Meat, Plasma, and Milk on a Q Exactive Focus LC-MS System
To describe a new method for veterinary drug analysis, showing how the variable data-independent acquisition (vDIA) workflow achieves high sensitivity and selectivity, providing a complete high-quality data record of the measured sample.
In a NACRW 2015 interview, Ed George discusses single methodology for the analysis of multi-class veterinary drugs in different animal matrices used for consumption.
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