The centrosome is an organelle that functions as the main microtubule organizing center (MTOC) of the cell and as a regulator of cell cycle progression. Centrosomes are found in higher eukaryotic cells, but not in fungi or plant cells, which use other structures to organize their microtubules. Each centrosome is made up of two centrioles surrounded by a mass of pericentriolar material (PCM), which contains the proteins that allow microtubule nucleation and anchoring. Generally, each centriole is a pinwheel of nine triplet microtubules. Cancer cells often have an abnormal number of centrosomes.
Centrosome marker antibodies detect proteins specific to the centrosome and can aid in the study of the structure and dynamics of the centrosome. Centrosome marker antibodies can also help elucidate the role or roles a protein may play in a number of tasks that are centered in or influenced by the centrosomes. Quality Invitrogen centrosome marker antibodies are available for a variety of research needs.