Exosomes are small vesicles composed of a lipid bilayer. Exosomes are formed when certain endosomes, called multivesicular bodies, fuse with the plasma membrane, releasing them into the extracellular environment. They may also be directly released from the plasma membrane.
Each exosome contains various cytoplasmic and membrane proteins in addition to lipids and RNA molecules. These components vary according to the exosome’s cell of origin. Exosomes are present in cell culture media and in body fluids such as blood, urine, saliva, amniotic fluid, and malignant ascites. Exosomes play important roles in processes like coagulation, waste management, and intercellular signaling. They are also of interest for clinical applications such as therapy, prognosis, and markers for disease. Learn more about exosome research.
Exosomal marker antibodies detect proteins specific to the exosomes and can aid in the study of the morphology and dynamics of the exosome. Exosomal marker antibodies can also help elucidate the role or roles a protein may play in a number of tasks that are centered in or influenced by the exosome. Quality Invitrogen exosomal marker antibodies are available for your research needs.