Gamma tubulin is ubiquitously expressed in eukaryotic cells, so it is often used as a loading control. It is an essential protein for cell growth and division, as it organizes microtubule arrays in the nucleus and cytoplasm.
Gamma tubulin is found primarily in centrosomes and spindle pole bodies where the most abundant microtubule nucleation occurs. In these microtubule organizing centers, gamma tubulin associates with several other proteins to form the gamma tubulin ring complex which provides scaffolding for alpha/beta tubulin dimers to begin polymerization. It also provides a cap that allows the microtubule to grow in the (+) direction.
Quality Invitrogen gamma tubulin antibodies are available for a variety of research needs, and most have been extensively validated for western blotting and immunostaining controls.