Custom POROS Resins
Unique capability in chromatography resin development
POROS® chromatography resins provide attributes that are well suited to downstream processing. These include a large surface area, high throughput, and robust physical stability.
When combined with user-defined affinity ligands, our resin development programs help deliver a high-speed, high-performance affinity chromatography solution tailored to your process requirements.
Start the process with your ligand, select from our library of existing CaptureSelect™ ligands, or generate a custom CaptureSelect™ ligand for your application.
Next, let us guide you to a pore size, ligand density, and coupling chemistry to optimize performance for your biotherapeutic. The resulting POROS® CaptureSelect™ affinity resin, not limited by diffusion, is designed to provide good dynamic binding capacity over a range of flow rates.
Capabilities and experience
We have been developing and manufacturing chromatography resins for more than two decades. Our experienced team of scientists and engineers has a successful track record in resin development, scale-up, and commercialization. Ligand- and resin-manufacturing facilities support the production of prototype affinity resins and scale-up to commercial lot sizes of 250 L.
Resin development includes the use of Design of Experiments (DoE) to define the resin manufacturing process required for your purification needs. All process validation and regulatory requirements are fully supported by an ISO 9001/13845 quality management system.
POROS CaptureSelect custom affinity resin process
Request a technical meeting
Unlock the power of POROS® affinity chromatography, and develop a platform purification process that reduces the number of processing steps and helps improve product yield.
Your local sales representative can arrange a technical meeting with our resin development scientists; simply submit a meeting request below.